VWF NM_000552.5(VWF):c.6554G>A (p.Arg2185Gln)

CI-VAR-00018534Explore in graph →p.Arg2185GlnNM_000552.5:c.6554G>AClinVar 100443 rs2229446

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
100443	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Hereditary von Willebrand disease; von Willebrand disease type 2; von Willebrand disease type 1; von Willebrand disease type 3; Thymoma; Lung cancer; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Clear cell carcinoma of kidney; Pancreatic adenocarcinoma; Colon adenocarcinoma; Gastric cancer; Cervical cancer	germline	9	Jun 30, 2025	clinvar