CDKN2A D108N

CI-VAR-00000403Explore in graph →CIViC 3288

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Unmapped disease1unmapped disease
CDKN2A D108N	(functional)	Functional	D	Supports Loss Of Function	2	submitted	EID9172 The CDKN2A variant D108N discovered in a melanoma patient was evaluated in in vivo experiments using transfected human fibroblasts. Co-immunoprecipitation experiments showed that D108N mutant p16 INK4… (full text at CIViC) PMID 12417717 · Huot et al., 2002 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.