CDKN2A c.151-1G>C

CI-VAR-00004894Explore in graph →CIViC 2884

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Melanoma1
CDKN2A c.151-1G>C	(predisposing)	Predisposing	C	Supports Predisposition	3	accepted	EID7765 Skipping of exon 2 of both the CDKN2A p14 and p16 isoform transcripts was detected by RT-PCR in a lymphoblastoid cell line derived from a patient carrying the c.151-1G>C variant. The novel CDKN2A spl… (full text at CIViC) PMID 11433531 · Petronzelli et al., 2001 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.