CCND1 P287T

CI-VAR-00003331Explore in graph →NP_444284.1:p.Pro287ThrNM_053056.3:c.859C>ACIViC 3571

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Unmapped disease1unmapped disease
CCND1 P287T	(functional)	Functional	D	Supports Gain Of Function	1	submitted	EID9781 A series of 60 endometrioid endometrial carcinomas were tested for CCND1 expression and amplification. Two samples with CCND1 expression measured via IHC were shown to have somatic mutations (P287S an… (full text at CIViC) PMID 12955092 · Moreno-Bueno et al., 2003 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.