NTRK1 Fusion

CI-VAR-00001527Explore in graph →CIViC 5511

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Undifferentiated Pleomorphic Sarcoma1
CCDC171::NTRK1 Fusion	(oncogenic)	Oncogenic	C	Supports Oncogenicity	1	submitted	EID13059 Dufresne et al. identified a CCDC171::NTRK1 fusion by whole-exome RNA sequencing in one undifferentiated pleomorphic sarcoma from an ambispective cohort of NTRK-rearranged mesenchymal tumors. The fusi… (full text at CIViC) PMID 37054503 · Dufresne et al., 2023 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.