BRCA1 M1I

CI-VAR-00002570Explore in graph →NP_009225.1:p.Met1IleNM_007294.3:c.3G>TClinVar 55072 CIViC 1237 rs80357475

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
55072	Pathogenic	reviewed by expert panel	3	Hereditary breast ovarian cancer syndrome; Breast-ovarian cancer, familial, susceptibility to, 1; Hereditary cancer-predisposing syndrome; Familial cancer of breast; Fanconi anemia, complementation group S; Pancreatic cancer, susceptibility to, 4; BRCA1-related disorder	germline	13	Jun 18, 2019	clinvar