BRCA1 E1559K

CI-VAR-00000667Explore in graph →NP_009225.1:p.Glu1559LysNM_007294.3:c.4675G>AClinVar 37604 CIViC 1243 rs80356988

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
37604	Pathogenic	reviewed by expert panel	3	Breast-ovarian cancer, familial, susceptibility to, 1; Hereditary cancer-predisposing syndrome; Hereditary breast ovarian cancer syndrome; BRCA1-related disorder	germline	18	Jun 18, 2019	clinvar