ALK G1202del

CI-VAR-00001589Explore in graph →NP_004295.2:p.Gly1202delNM_004304.5:c.3605_3607delCIViC 2813

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Lung Non-Small Cell Carcinoma1
EML4::ALK Fusion AND ALK G1202del	Ceritinib	Predictive	C	Supports Resistance	4	submitted	EID7599 In an analysis of 83 ALK positive NSCLC patients treated with multiple ALK inhibitors, one patient biopsy showed G1202del mutation after progressing on ceritinib. In addition, Ba/F3 cell lines express… (full text at CIViC) PMID 27432227 · Gainor et al., 2016 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.