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Clinical trials
Studies registered on ClinicalTrials.gov whose conditions were reconciled to the cancer taxonomy. Status and phase are as posted by the registrant.
380 studies match
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06311721 | A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer | active not recruiting | Phase 3 | 315 | AmgenINDUSTRY | 23 | May 6, 2026 | clinicaltrials |
| NCT06117774 | Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)(DeLLphi-306) | active not recruiting | Phase 3 | 404 | AmgenINDUSTRY | 27 | Apr 29, 2026 |
| NCT05975073 | A Phase 1/2 Study of Anvumetostat in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors | completed | Phase 1 / Phase 2 | 53 | AmgenINDUSTRY | 7 | Apr 22, 2026 | clinicaltrials |
| NCT03937154 | Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer | active not recruiting | Phase 3 | 145 | AmgenINDUSTRY | 18 | Apr 7, 2026 | clinicaltrials |
| NCT07143513 | Real World Evaluation of Sotorasib Among Chinese Non-Small Cell Lung Cancer Patients | completed | — | 102 | AmgenINDUSTRY | 1 | Apr 7, 2026 | clinicaltrials |
| NCT06430866 | Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)(Eucalyptus) | active not recruiting | Phase 3 | 163 | AmgenINDUSTRY | 18 | Apr 1, 2026 | clinicaltrials |
| NCT05907122 | A Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma | completed | Phase 3 | 256 | AmgenINDUSTRY | 22 | Mar 27, 2026 | clinicaltrials |
| NCT05800964 | Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors | completed | Phase 1 | 37 | AmgenINDUSTRY | 9 | Feb 17, 2026 | clinicaltrials |
| NCT03362177 | Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer(RECITE) | completed | Phase 3 | 165 | AmgenINDUSTRY | 20 | Feb 11, 2026 | clinicaltrials |
| NCT02910557 | Postmarketing Prospective Study of Melanoma Patients Treated With IMLYGIC® to Characterize Risk of Herpetic Infection | completed | — | 187 | AmgenINDUSTRY | 5 | Feb 5, 2026 | clinicaltrials |
| NCT06054113 | Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL) | active not recruiting | Phase 2 | 18 | AmgenINDUSTRY | 1 | Jan 27, 2026 | clinicaltrials |
| NCT06054555 | A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma | active not recruiting | Phase 3 | 633 | AmgenINDUSTRY | 31 | Jan 12, 2026 | clinicaltrials |
| NCT05740566 | Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer(DeLLphi-304) | active not recruiting | Phase 3 | 509 | AmgenINDUSTRY | 31 | Jan 5, 2026 | clinicaltrials |
| NCT06211036 | Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab(DeLLphi-305) | active not recruiting | Phase 3 | 563 | AmgenINDUSTRY | 29 | Dec 17, 2025 | clinicaltrials |
| NCT03319940 | Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) | active not recruiting | Phase 1 | 269 | AmgenINDUSTRY | 13 | Nov 19, 2025 | clinicaltrials |
| NCT04185883 | Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101) | active not recruiting | Phase 1 | 610 | AmgenINDUSTRY | 13 | Oct 22, 2025 | clinicaltrials |
| NCT03792841 | Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC | terminated | Phase 1 | 212 | AmgenINDUSTRY | 10 | Oct 16, 2025 | clinicaltrials |
| NCT03392064 | A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC | suspended | Phase 1 | 6 | AmgenINDUSTRY | 1 | Oct 15, 2025 | clinicaltrials |
| NCT04117958 | Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers | terminated | Phase 1 | 58 | AmgenINDUSTRY | 9 | Oct 14, 2025 | clinicaltrials |
| NCT04362748 | Study of AMG 256 in Adult Subjects With Advanced Solid Tumors | completed | Phase 1 | 34 | AmgenINDUSTRY | 4 | Oct 7, 2025 | clinicaltrials |
| NCT04586660 | Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone | active not recruiting | Phase 4 | 36 | AmgenINDUSTRY | 2 | Oct 1, 2025 | clinicaltrials |
| NCT04885998 | AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC) | completed | Phase 1 | 23 | AmgenINDUSTRY | 6 | Sep 29, 2025 | clinicaltrials |
| NCT04702737 | A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer(DeLLpro-300) | completed | Phase 1 | 41 | AmgenINDUSTRY | 9 | Sep 12, 2025 | clinicaltrials |
| NCT03836053 | Assessment of AMG 420 in Subjects With Relapsed and/or Refractory Multiple Myeloma(AMG420) | terminated | Phase 1 | 23 | AmgenINDUSTRY | 5 | Sep 11, 2025 | clinicaltrials |
| NCT03284879 | Post-Marketing Surveillance Study of OTEZLA | completed | — | 1,086 | AmgenINDUSTRY | 1 | Sep 8, 2025 | clinicaltrials |
| NCT04191616 | Study of Early Relapsed, Lenalidomide-refractory Subjects Eligible for Carfilzomib Triplet(SELECT) | completed | Phase 2 | 54 | AmgenINDUSTRY | 8 | Sep 4, 2025 | clinicaltrials |
| NCT03853109 | AMG 404 in Patients With Advanced Solid Tumors | completed | Phase 1 | 171 | AmgenINDUSTRY | 13 | Jul 20, 2025 | clinicaltrials |
| NCT05209152 | AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia | terminated | Phase 1 | 7 | AmgenINDUSTRY | 1 | Jul 14, 2025 | clinicaltrials |
| NCT04740034 | A Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma | terminated | Phase 1 | 42 | AmgenINDUSTRY | 1 | Jun 17, 2025 | clinicaltrials |
| NCT02303821 | Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia | completed | Phase 1 | 141 | AmgenINDUSTRY | 33 | Jun 4, 2025 | clinicaltrials |
| NCT04506086 | Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL) | terminated | Phase 4 | 10 | AmgenINDUSTRY | 1 | May 18, 2025 | clinicaltrials |
| NCT03158688 | Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.(CANDOR) | completed | Phase 3 | 466 | AmgenINDUSTRY | 19 | May 9, 2025 | clinicaltrials |
| NCT05267470 | A Study of Bemarituzumab Monotherapy and Combination With Other Anti-cancer Therapy in SqNSCLC With FGFR2b Overexpression (FORTITUDE-201)(FORTITUDE-201) | terminated | Phase 1 | 74 | AmgenINDUSTRY | 8 | Mar 25, 2025 | clinicaltrials |
| NCT06064500 | Tarlatamab (AMG 757) Expanded Access Protocol for Advanced Small Cell Lung Cancer | approved for marketing | — | — | AmgenINDUSTRY | 4 | Mar 10, 2025 | clinicaltrials |
| NCT06784778 | Observational Study of Patients With Advanced Melanoma (Skin Cancer) to Assess if IOpener®-Melanoma Test Can Predict Response to Immunotherapy.(COMO) | recruiting | — | 196 | Pamgene International B.V.INDUSTRY | 1 | Feb 28, 2025 | clinicaltrials |
| NCT02345408 | Phase 1b Study of CCX872-B in Patients With Pancreatic Adenocarcinoma | completed | Phase 1 | 54 | AmgenINDUSTRY | 2 | Feb 27, 2025 | clinicaltrials |
| NCT04727554 | Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors | completed | Phase 1 | 11 | AmgenINDUSTRY | 10 | Jan 6, 2025 | clinicaltrials |
| NCT00597909 | Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy | terminated | Phase 2 | 1 | AmgenINDUSTRY | 1 | Dec 17, 2024 | clinicaltrials |
| NCT03296696 | Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma | terminated | Phase 1 | 30 | AmgenINDUSTRY | 6 | Oct 29, 2024 | clinicaltrials |
| NCT03340766 | Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)(HARBOUR) | completed | Phase 1 | 31 | AmgenINDUSTRY | 6 | Oct 17, 2024 | clinicaltrials |
| NCT03541369 | Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia(20170528) | terminated | Phase 1 | 64 | AmgenINDUSTRY | 6 | Oct 10, 2024 | clinicaltrials |
| NCT02939183 | Phase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma(INTREPID-1) | completed | Phase 1 | 61 | AmgenINDUSTRY | 4 | Sep 26, 2024 | clinicaltrials |
| NCT03859427 | A Study Comparing Once-weekly vs Twice-weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma(ARROW2) | completed | Phase 3 | 454 | AmgenINDUSTRY | 17 | Aug 13, 2024 | clinicaltrials |
| NCT02509507 | Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611(MASTERKEY-318) | completed | Phase 1 / Phase 2 | 127 | AmgenINDUSTRY | 9 | Aug 6, 2024 | clinicaltrials |
| NCT02520427 | A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies | terminated | Phase 1 | 95 | AmgenINDUSTRY | 4 | Jul 31, 2024 | clinicaltrials |
| NCT04822298 | Study of AMG 160 in Subjects With Non-Small Cell Lung Cancer | terminated | Phase 1 | 3 | AmgenINDUSTRY | 3 | Jul 5, 2024 | clinicaltrials |
Data updated 23 days agoSource updated unknownsource: clinicaltrials