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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
437 stopped studies mapped to Squamous Cell Carcinoma and descendants · 91% state a reason
Over the 437 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02254044 | Dose Escalation of Bivatuzumab Mertansine in Patients With Advanced Squamous Cell… | Phase 1 | terminated | Oct 1, 2014 | Boehringer Ingelheim | not stated | Not stated |
| NCT01718223 | Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent… | N/A | withdrawn | Oct 31, 2012 | Roswell Park Cancer Institute | implementation issues | Other (stated, no rule matched) |
| NCT01305772 | Identification of Gene Expression Signature for Panitumumab Sensitivity in Untreated…(TOP0901) | Phase 2 | terminated | Mar 1, 2011 | Neal Ready | This study was terminated for low accrual. | Enrollment / accrual |
| NCT01682031 | Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck… | Phase 2 | terminated | Sep 10, 2012 | Roswell Park Cancer Institute | Due to a lack of funding | Funding |
| NCT01175499 | Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper…(TNFE-NBI) | N/A | withdrawn | Aug 4, 2010 | University of California, San Francisco | Unable to obtain funding to continue recruitment; no accrual | Enrollment / accrual |
| NCT00911326 | Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma | Phase 3 | terminated | Jun 1, 2009 | Navidea Biopharmaceuticals | The trial was terminated early based on an interim review by the Data and Safety Monitoring… | Safety / toxicity |
| NCT01491633 | Dasatinib in Advanced Squamous Cell Lung Cancer | Phase 2 | terminated | Dec 14, 2011 | Dana-Farber Cancer Institute | Safety issues/concerns per DF/HCC PI | Safety / toxicity |
| NCT01360827 | EMD 1201081 + 5-FU + Cisplatin + Cetuximab in Subjects With Recurrent / Metastatic… | Phase 1 | terminated | May 26, 2011 | Merck KGaA, Darmstadt, Germany | Study terminated due to potential safety concerns in combination with platinum-based therapies | Safety / toxicity |
| NCT00112905 | Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium | Phase 2 | terminated | Jun 3, 2005 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00596830 | Carboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced… | Phase 3 | terminated | Jan 17, 2008 | Pfizer | See termination reason in detailed description. | Other (stated, no rule matched) |
| NCT01728480 | Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer… | Phase 1 | withdrawn | Nov 19, 2012 | Roswell Park Cancer Institute | Financial Sponsor requested termination | Funding |
| NCT00095641 | S0225 Capecitabine in Treating Patients Who Have Undergone Surgery for Locally Recurrent… | Phase 2 | withdrawn | Nov 8, 2004 | SWOG Cancer Research Network | no longer studying this disease site | Other (stated, no rule matched) |
| NCT00673049 | Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer(NSCLC) | Phase 3 | terminated | May 7, 2008 | Pfizer | See termination reason in detailed description. | Other (stated, no rule matched) |
| NCT00906360 | Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or… | Phase 1 | terminated | May 21, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01674374 | Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have… | Phase 2 | withdrawn | Aug 28, 2012 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00042835 | Erlotinib and Radiation Therapy Plus Combination Chemotherapy in Treating Patients With… | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00033449 | Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage… | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00081211 | Intratumoral PV701 in Treating Patients With Advanced or Recurrent Unresectable Squamous… | Phase 1 | terminated | Apr 8, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT01015664 | Combination of Cisplatin, Cetuximab and Temsirolimus in Recurrent or Metastatic Squamous… | Phase 1 / Phase 2 | terminated | Nov 18, 2009 | University of Tennessee Cancer Institute | not stated | Not stated |
| NCT01415986 | Interstitial Photodynamic Therapy (PDT) With Temoporfin for Advanced Head and Neck Cancers | Phase 2 | terminated | Aug 12, 2011 | University of Arkansas | The patient was "lost to follow-up" and the PI left the institution. | Investigator |
| NCT00427102 | MRX, Radiation, and Chemotherapy for Patients With Resected Squamous Cell Carcinoma of… | Phase 1 | terminated | Jan 26, 2007 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | No subjects enrolled and PI went to another facility | Enrollment / accrual |
| NCT00038038 | Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole | N/A | withdrawn | May 27, 2002 | M.D. Anderson Cancer Center | No participants enrolled, study terminated. | Enrollment / accrual |
| NCT00605709 | Dose-Ranging Safety and Efficacy Study of Topical Creams Containing API 31510 for the… | Phase 2 | withdrawn | Jan 31, 2008 | BPGbio | not stated | Not stated |
| NCT00368329 | Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced… | Phase 1 | terminated | Aug 24, 2006 | Stanford University | low accrual | Enrollment / accrual |
| NCT01491139 | Phase I Study of Olaparib With Cisplatin Based Chemoradiotherapy in Squamous Cell…(ORCA) | Phase 1 | withdrawn | Dec 13, 2011 | University College, London | Study stopped due to issues surrounding development and formulation of olaparib | Other (stated, no rule matched) |
| NCT00363441 | A Study of Conventional 3D Radiation vs. Intensity-Modulated Radiation in Squamous Cell… | Phase 2 / Phase 3 | withdrawn | Aug 15, 2006 | Alberta Health services | not stated | Not stated |
| NCT00401401 | Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck Cancer | Phase 1 / Phase 2 | terminated | Nov 20, 2006 | Genmab | MTD was established and patients completed 16 months safety f-up and response assessments. It is… | Safety / toxicity |
| NCT00937300 | T-cell Based Immunotherapy for Head and Neck Cancer | Phase 1 | withdrawn | Jul 13, 2009 | Inge Marie Svane | The patients eligible for this trial do not exist anymore due to change in procedures. | Other (stated, no rule matched) |
| NCT00805012 | Docetaxel and S-1 in Head and Neck Squamous Cell Carcinoma (HNSCC) | Phase 2 | terminated | Dec 9, 2008 | Seoul National University Hospital | slow accrual rate | Enrollment / accrual |
| NCT00563862 | Benefit of Adding Chemotherapy And/Or Modification of Radiotherapy Schedule for Advance… | N/A | terminated | Nov 26, 2007 | Hospital Authority, Hong Kong | not stated | Not stated |
| NCT01363466 | Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer | Phase 3 | terminated | Jun 1, 2011 | UNICANCER | low recruitment | Enrollment / accrual |
| NCT01077869 | A Feasibility Study on the Use of F-18-FDG-PET and Optical Imaging in Evaluation of… | — | terminated | Mar 1, 2010 | University Hospital, Ghent | poor recruitment rate | Enrollment / accrual |
| NCT00233636 | Iressa and Radiotherapy in the Treatment of the Locally Advanced Inoperable Squamous Cell… | Phase 2 | withdrawn | Oct 6, 2005 | AstraZeneca | not stated | Not stated |
| NCT00472706 | Trial of Excision Versus Photodynamic Therapy in the Treatment of Bowen's Disease | Phase 4 | terminated | May 14, 2007 | Catharina Ziekenhuis Eindhoven | Study stopped because of disappointing inclusion rates | Other (stated, no rule matched) |
| NCT00909558 | Safety and Effectiveness Study of Autologous Natural Killer and Natural Killer T Cells on… | Phase 1 | suspended | May 28, 2009 | Envita Medical Center, Inc. | not stated | Not stated |
| NCT00239200 | Lapatinib (GW572016) for Metastatic or Recurrent Squamous Cell Carcinoma Esophagus | Phase 2 | terminated | Oct 14, 2005 | University of Michigan Rogel Cancer Center | notification from sponsor | Other (stated, no rule matched) |
| NCT00559351 | RCT on the Combined Modality Treatment of Squamous Cell Carcinoma of the Esophagus | Phase 3 | terminated | Nov 16, 2007 | Ministry of Scientific Research and Information Technology, Poland | difficulty in recruitment | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Oct 1, 2014source: clinicaltrials