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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
58 stopped studies mapped to Myeloproliferative Neoplasm, BCR-ABL1 Negative and descendants · 86% state a reason
Over the 58 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01291784 | Anti-TGF-beta Therapy in Patients With Myelofibrosis | Phase 1 | terminated | Feb 8, 2011 | John Mascarenhas | Early termination when the drug was no longer made available by the pharmaceutical company due to… | Sponsor / business decision |
| NCT00940784 | Clopidogrel and Aspirin for the Treatment of Polycythemia Vera(ISCLAP) | Phase 2 | withdrawn | Jul 16, 2009 | Ronald Hoffman | Could not get drug | Other (stated, no rule matched) |
| NCT00594308 | In-Vivo Activated T-Cell Depletion to Prevent GVHD | N/A | terminated | Jan 15, 2008 | Indiana University | Treatment ineffective | Other (stated, no rule matched) |
| NCT00387426 | Sunitinib in Treating Patients With Idiopathic Myelofibrosis | Phase 2 | terminated | Oct 13, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00393380 | Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an… | Phase 2 | terminated | Oct 27, 2006 | The Emmes Company, LLC | Study stopped because of toxicity concerns. | Safety / toxicity |
| NCT01645124 | Large-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV)(CYTO-PV) | Phase 3 | terminated | Jul 20, 2012 | Consorzio Mario Negri Sud | Low accrual rate not allowing planned sample size leads to a futility condition | Efficacy / futility |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT00522574 | A Safety Study of XL019 in Adults With Myelofibrosis | Phase 1 | terminated | Aug 29, 2007 | Exelixis | Due to emerging safety data | Safety / toxicity |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Dec 8, 2014source: clinicaltrials