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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
409 stopped studies mapped to Mature B-Cell Non-Hodgkin Lymphoma and descendants · 88% state a reason
Over the 409 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01170052 | Bendamustine and Temsirolimus in Patients With Relapsed or Refractory Mantle Cell… | Phase 1 / Phase 2 | withdrawn | Jul 27, 2010 | Charite University, Berlin, Germany | insufficient enrollment | Enrollment / accrual |
| NCT01116154 | Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin… | Phase 1 | terminated | May 4, 2010 | City of Hope Medical Center | Sponsor withdrew support for the study | Other (stated, no rule matched) |
| NCT00386321 | Yt90 Zevalin and Combination Chemotherapy (Z-CHOP)in Treating Patients With Stage II,… | Phase 2 | terminated | Oct 11, 2006 | Chulalongkorn University | Participants are no longer being examined or treated. | Other (stated, no rule matched) |
| NCT00136591 | A Phase 2 Study of Velcade™ in Subjects With Relapsed or Refractory Follicular B-Cell… | Phase 2 | terminated | Aug 29, 2005 | Lymphoma Study Association | An arm closed due to lack of efficacy | Efficacy / futility |
| NCT00275262 | A Study to Evaluate the Ability of Lupron Depot to Enhance Immune Function Following Bone… | Phase 2 | terminated | Jan 11, 2006 | Abbott | not stated | Not stated |
| NCT00474188 | A Study to Evaluate Lenalidomide Combined With Dexamethasone in Relapsed or Refractory… | Phase 2 | terminated | May 16, 2007 | Celgene Corporation | Business decision | Sponsor / business decision |
| NCT00234481 | Safety Study of XL844 in Subjects With Chronic Lymphocytic Leukemia | Phase 1 | terminated | Oct 7, 2005 | Exelixis | Study closed due to slow enrollment | Enrollment / accrual |
| NCT00180895 | Rituximab in Children and Adolescents With Relapsed and Refractory B-Cell NHL/L3ALL | Phase 2 | terminated | Sep 16, 2005 | Gustave Roussy, Cancer Campus, Grand Paris | not stated | Not stated |
| NCT00083473 | A Pilot Study of Pivanex in Patients With Chronic Lymphocytic Leukemia | Phase 2 | terminated | May 26, 2004 | Titan Pharmaceuticals | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Mar 16, 2011source: clinicaltrials