Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
840 stopped studies mapped to Malignant Prostate Neoplasm and descendants · 92% state a reason
Over the 840 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00798837 | Intraprostatic MAXimal Simultaneous Boost | N/A | terminated | Nov 26, 2008 | British Columbia Cancer Agency | Excess risk in rectal bleeding of first 10 patients | Other (stated, no rule matched) |
| NCT00634582 | Paricalcitol in Treating Patients With Advanced Prostate Cancer and Bone Metastases | Phase 2 | terminated | Mar 13, 2008 | Wake Forest University Health Sciences | slow accrual | Enrollment / accrual |
| NCT02252978 | Ciprofloxacin Compared to Placebo in Diagnosing Prostate Cancer in Patients Undergoing… | Phase 2 | withdrawn | Sep 30, 2014 | Wake Forest University Health Sciences | No funding support | Funding |
| NCT00996749 | Omega-3 Fatty Acids in Treating Patients With Advanced Prostate Cancer | N/A | withdrawn | Oct 16, 2009 | Wake Forest University Health Sciences | No Participants enrolled; slow accrual | Enrollment / accrual |
| NCT01724619 | Update and Biodistribution of [F-18]FMDHT pET/CT in Normal Healthy Volunteers and… | Early Phase 1 | terminated | Nov 12, 2012 | Wake Forest University Health Sciences | Study tracer can no longer be obtained at our institution | Other (stated, no rule matched) |
| NCT01644136 | Microspheres in Preventing Lymphatic Fluid Collection After Surgery in Patients With… | N/A | terminated | Jul 18, 2012 | Ohio State University Comprehensive Cancer Center | PI left institution | Investigator |
| NCT02215161 | Selinexor in Treating Patients With Abiraterone Acetate and/or Enzalutamide Refractory… | Phase 2 | terminated | Aug 13, 2014 | University of California, San Francisco | Risk to benefit ratio is not acceptable | Other (stated, no rule matched) |
| NCT01845792 | Study of Abiraterone Acetate and Prednisone in Combination With Cabazitaxel in Patients… | Phase 2 | terminated | May 3, 2013 | University of Colorado, Denver | Low accrual | Enrollment / accrual |
| NCT01987193 | Feasibility Study of Tumor Blood Flow Measurement by Detection of Positron Activation… | — | terminated | Nov 19, 2013 | University of Florida | Slow accrual; funding stopped | Enrollment / accrual |
| NCT01522443 | Study of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously…(COMET-2) | Phase 3 | terminated | Jan 31, 2012 | Exelixis | Stopped after the outcome of cabozantinib Phase 3 CRPC study XL184-307. | Other (stated, no rule matched) |
| NCT02284971 | Pilot Study of SBRT and CDX-1127 in Prostate Cancer(Prostate-04) | Phase 1 | terminated | Nov 6, 2014 | James Larner, MD | Low accruals | Enrollment / accrual |
| NCT02206724 | Prospective Evaluation of Stereotactic Body Radiotherapy for Metastatic Prostate Cancer | N/A | withdrawn | Aug 1, 2014 | Sharp HealthCare | Unable to enroll patients | Enrollment / accrual |
| NCT02441517 | A Study of Enzalutamide Re-treatment in Metastatic Castration-resistant Prostate Cancer… | Phase 4 | terminated | May 12, 2015 | Astellas Pharma Global Development, Inc. | The study is closed early due to lck of enrollment. | Enrollment / accrual |
| NCT00096304 | Epirubicin and Docetaxel in Treating Patients With Metastatic Prostate Cancer | Phase 1 | terminated | Nov 9, 2004 | Medical University of South Carolina | Low accrual | Enrollment / accrual |
| NCT00860158 | Neoadjuvant Dasatinib Plus LHRH Analogue Therapy in High-Risk Localized Prostate Cancer | Phase 2 | terminated | Mar 12, 2009 | Noah Hahn, M.D. | Slow accrual; closed by funder | Enrollment / accrual |
| NCT01188408 | Efficacy and Safety Study of LE-DT to Treat Metastatic Castrate Resistant Prostate Cancer | Phase 2 | withdrawn | Aug 25, 2010 | INSYS Therapeutics Inc | Study shut-down in 12/2010 when NeoPharm merged with Insys. | Other (stated, no rule matched) |
| NCT01859338 | Soft Tissue Detection on MRI, Cone Beam CT and Fan Beam CT and Integration of Functional… | — | terminated | May 21, 2013 | Virginia Commonwealth University | Slow accrual | Enrollment / accrual |
| NCT02349139 | Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate… | Phase 1 | terminated | Jan 28, 2015 | Asana BioSciences | Business Decision | Sponsor / business decision |
| NCT00004261 | EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or… | Phase 1 | terminated | Dec 11, 2003 | University Health Network, Toronto | Lack of patient accrual | Enrollment / accrual |
| NCT00638378 | Study of Ruxolitinib (INCB018424) Administered Orally to Patients With Androgen… | Phase 2 | terminated | Mar 19, 2008 | Incyte Corporation | According to the protocol, the sponsor terminated the study after it was determined that less than… | Other (stated, no rule matched) |
| NCT02546427 | Hypofractionated Whole Pelvic Radiotherapy of the Prostate | N/A | withdrawn | Sep 10, 2015 | Albert J. Chang | PI left UCSF and the study was closed without any accruals. | Investigator |
| NCT00003516 | Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | Slow accrual | Enrollment / accrual |
| NCT00003534 | Antineoplaston Therapy in Treating Patients With Refractory Stage IV Prostate Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | No participants enrolled. | Enrollment / accrual |
| NCT00447616 | Prostatectomy Prospective Database | — | terminated | Mar 15, 2007 | Kenneth Peters, MD | Lack of funding | Funding |
| NCT00918645 | Calcium-41 (41Ca) Chloride Aqueous Solution in Diagnosing Patients With Prostate Cancer…(UCDCC#217) | N/A | terminated | Jun 11, 2009 | University of California, Davis | not stated | Not stated |
| NCT02131207 | MRI Before Biopsy in Diagnosing Patients With Prostate Cancer | — | terminated | May 6, 2014 | Case Comprehensive Cancer Center | Principal Investigator Left Institution | Investigator |
| NCT00769990 | Genistein in Treating Patients Undergoing External-Beam Radiation Therapy for Bone… | Phase 1 / Phase 2 | withdrawn | Oct 9, 2008 | Masonic Cancer Center, University of Minnesota | No patient accrual. | Enrollment / accrual |
| NCT00003533 | Antineoplaston Therapy in Treating Patients With Metastatic Prostate Cancer | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | Slow accrual | Enrollment / accrual |
| NCT00348816 | Docetaxel, Radiation Therapy, and Prednisone in Treating Patients Who Have Undergone… | Phase 2 | terminated | Jul 6, 2006 | The University of Texas Health Science Center at San Antonio | Loss of funding | Funding |
| NCT01200810 | Bicalutamide and RO4929097 in Treating Patients With Previously Treated Prostate Cancer | Phase 2 | terminated | Sep 14, 2010 | National Cancer Institute (NCI) | Drug was no longer available | Other (stated, no rule matched) |
| NCT01260909 | Real-Time MV/kV Image Guided Radiation Therapy | — | withdrawn | Dec 15, 2010 | Stanford University | Business decision | Sponsor / business decision |
| NCT00524589 | Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not… | Phase 2 | terminated | Sep 3, 2007 | Roswell Park Cancer Institute | closed due to futility | Efficacy / futility |
| NCT02793219 | Provenge Followed by Docetaxel in Castration-Resistant Prostate Cancer | Phase 2 | withdrawn | Jun 8, 2016 | The University of Texas Health Science Center, Houston | Dendreon was sold and new company decided not to fund study. | Funding |
| NCT02793765 | Docetaxel Followed by Provenge in Metastatic Prostate Cancer | Phase 2 | withdrawn | Jun 8, 2016 | The University of Texas Health Science Center, Houston | Dendreon was sold and new company decided not to fund study. | Funding |
| NCT01748890 | A Pilot Trial of Sonoelastography for Planning Tumor-targeted Prostate Biopsy | N/A | terminated | Dec 13, 2012 | Massachusetts General Hospital | Insufficient recruitment | Enrollment / accrual |
| NCT02564549 | MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk… | N/A | terminated | Sep 30, 2015 | Virginia Commonwealth University | Study halted prematurely and will not resume | Other (stated, no rule matched) |
| NCT02232672 | Choline PET/CT vs. MeAIB PET/CT in Prostate Cancer | N/A | withdrawn | Sep 5, 2014 | Odense University Hospital | not stated | Not stated |
| NCT00480857 | Salvage Radiation Therapy and Taxotere for PSA Failure After Radical Prostatectomy | Phase 2 | terminated | May 31, 2007 | University of Michigan Rogel Cancer Center | Lack of funding. | Funding |
| NCT03173807 | Prostate Nutrition and Exercise STudy (ProNEST)(ProNEST) | N/A | withdrawn | Jun 2, 2017 | University of Pittsburgh | Unable to find adequate funding | Funding |
| NCT01145508 | Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With… | Phase 2 | terminated | Jun 16, 2010 | National Cancer Institute (NCI) | Poor accrual | Enrollment / accrual |
| NCT02454595 | Registry to Measure the Impact of Adding Genomic Testing | — | terminated | May 27, 2015 | Myriad Genetic Laboratories, Inc. | lack of enrollment | Enrollment / accrual |
| NCT01866423 | Orteronel in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer | Phase 2 | terminated | May 31, 2013 | University of Southern California | Not progressing toward scientific goals | Other (stated, no rule matched) |
| NCT01677845 | Hypo-Fractionated Radiation Therapy for Localized Prostate Cancer | Phase 1 | terminated | Sep 3, 2012 | NYU Langone Health | PI no longer with the institution | Other (stated, no rule matched) |
| NCT02810886 | Prospective Evaluation of 68Ga-PSMA PET-CT for Recurrence Detection of Prostate Cancer…(ProsPERo) | Phase 2 | withdrawn | Jun 23, 2016 | Jules Bordet Institute | Recent publications demonstrating the clinical interest in performing 68Ga-PSMA for recurrence… | Other (stated, no rule matched) |
| NCT00898833 | Plasma and Urine Samples From Patients With Hormone-Refractory Prostate Cancer Enrolled… | — | terminated | May 12, 2009 | Alliance for Clinical Trials in Oncology | The proposed work could not be completed. | Other (stated, no rule matched) |
| NCT02307552 | Transurethral Ultrasonic Imaging For Detection and Classification of Prostate Cancer | N/A | terminated | Dec 4, 2014 | University of California, Irvine | The probe could not be anchored in place and would rotate about its axis, thus comparison was… | Other (stated, no rule matched) |
| NCT02042053 | PET/MR Assessment of Sipuleucel T Treatment for Metastatic Castration Resistant Prostate… | N/A | terminated | Jan 22, 2014 | NYU Langone Health | Due to PI leaving the institution | Other (stated, no rule matched) |
| NCT00003622 | Vinorelbine Plus Paclitaxel in Treating Patients With Metastatic Prostate Cancer That Is… | Phase 2 | withdrawn | May 3, 2004 | James Ahlgren | No recruitment | Enrollment / accrual |
| NCT03211052 | A Study of Neoadjuvant TAK-700 and Leuprorelin Acetate Followed by Surgery Versus Surgery…(NEPTUNE) | Phase 2 | terminated | Jul 7, 2017 | Centre of Experimental Medicine | IMP no longer available | Other (stated, no rule matched) |
| NCT00536991 | Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating… | Phase 1 / Phase 2 | terminated | Sep 28, 2007 | Roswell Park Cancer Institute | difficult to recruit | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jul 11, 2018source: clinicaltrials