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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
2,061 stopped studies mapped to Malignant Neoplasm of Unknown Primary and descendants · 91% state a reason
Over the 2,061 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00148135 | Combination of Carboplatin, Gemcitabine, and Capecitabine in Patients With Carcinoma of… | Phase 2 | terminated | Sep 7, 2005 | University of Michigan Rogel Cancer Center | recruitment goals met | Enrollment / accrual |
| NCT00417677 | A Study Combining Treatment With Temsirolimus and Sunitinib for Subjects With Advanced… | Phase 1 / Phase 2 | terminated | Jan 4, 2007 | Wyeth is now a wholly owned subsidiary of Pfizer | Decision was made not to attempt a lower dose | Other (stated, no rule matched) |
| NCT00131651 | ATN-161 in Advanced Renal Cell Cancer | Phase 2 | terminated | Aug 19, 2005 | Attenuon | not stated | Not stated |
| NCT00559351 | RCT on the Combined Modality Treatment of Squamous Cell Carcinoma of the Esophagus | Phase 3 | terminated | Nov 16, 2007 | Ministry of Scientific Research and Information Technology, Poland | difficulty in recruitment | Enrollment / accrual |
| NCT00514332 | Comparison Between Colorectal Stents and Primary Surgery in Obstructive Colonic Cancer. A… | N/A | terminated | Aug 9, 2007 | University Hospital, Montpellier | enrolling participants stopped | Enrollment / accrual |
| NCT00116389 | Trial of Talabostat and Gemcitabine in Patients With Stage IV Adenocarcinoma of the… | Phase 2 | terminated | Jun 29, 2005 | Point Therapeutics | FDA Hold May 2007 | Other (stated, no rule matched) |
| NCT00316433 | Oxaliplatin/CPT-11 for Extensive Stage Small Cell Lung Cancer | Phase 2 | terminated | Apr 20, 2006 | Swedish Medical Center | not stated | Not stated |
| NCT00355212 | Comparison Between Radiofrequency Versus Ethanol Injection for the Treatment of… | Phase 3 | terminated | Jul 21, 2006 | Azienda Ospedaliera San Giovanni Battista | not stated | Not stated |
| NCT00151645 | Efficacy of Activated Lymphocytes in Renal Cell Carcinoma. | Phase 2 | terminated | Sep 9, 2005 | Rennes University Hospital | not stated | Not stated |
| NCT00034333 | Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads Vs. IV Doxorubicin in… | Phase 2 / Phase 3 | terminated | Apr 26, 2002 | FeRx | not stated | Not stated |
| NCT00057382 | T138067 Versus Doxorubicin in Chemotherapy-Naive, Unresectable, Hepatocellular Carcinoma… | Phase 2 / Phase 3 | terminated | Apr 2, 2003 | Tularik | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Jan 10, 2008source: clinicaltrials