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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
2,225 stopped studies mapped to Malignant Genitourinary System Neoplasm and descendants · 88% state a reason
Over the 2,225 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01639521 | Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine,… | Phase 2 | withdrawn | Jul 12, 2012 | University of Southern California | Lack of funding | Funding |
| NCT01677390 | A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell… | Phase 1 | terminated | Sep 3, 2012 | Seagen Inc. | not stated | Not stated |
| NCT00479635 | A Phase II Trial of TPI 287 in Patients With Metastatic Prostate Cancer | Phase 2 | terminated | May 28, 2007 | Cortice Biosciences, Inc. | Sponsor could no longer support; enrollment stopped August 2008. | Enrollment / accrual |
| NCT01403103 | Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer | Early Phase 1 | withdrawn | Jul 27, 2011 | Case Comprehensive Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT00922129 | Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in… | Phase 2 / Phase 3 | withdrawn | Jun 17, 2009 | St. Joseph's Healthcare Hamilton | Study did not start up as planned. | Other (stated, no rule matched) |
| NCT01000948 | A Safety Study of ZD4054 in Prior Chemotherapy Treated Patients With Metastatic…(DAPROCA-1) | Phase 2 | terminated | Oct 23, 2009 | Aarhus University Hospital | A consequence of the results of the ENTHUSE phase III study program | Other (stated, no rule matched) |
| NCT01202890 | Study of Revlimid With Doxil and Avastin for Patients With Platinum Resistant Ovarian… | Phase 1 | terminated | Sep 16, 2010 | New Mexico Cancer Research Alliance | Terminated due to inadequate rate of accrual. | Enrollment / accrual |
| NCT00917865 | FACBC Positron Emission Tomography/Computed Tomography(PET/CT) Used in the Diagnosis of… | Phase 2 | terminated | Jun 10, 2009 | David M. Schuster, MD | Optimal histolgic verification support such as whole mount analysis could not be made available. | Other (stated, no rule matched) |
| NCT00176501 | Irradiated Donor Lymphocytes in Treating Patients With Metastatic Kidney Cancer | Phase 2 | terminated | Sep 15, 2005 | Rutgers, The State University of New Jersey | Slow accrual | Enrollment / accrual |
| NCT01131039 | Safety and Efficacy Study of Gemcitabine Plus Bevacizumab in Patients With… | Phase 2 | withdrawn | May 26, 2010 | Emory University | PI left Emory | Investigator |
| NCT00014287 | Gemcitabine in Treating Patients With Recurrent or Refractory Bladder Cancer | Phase 1 | withdrawn | Jan 7, 2004 | University of Pittsburgh | not stated | Not stated |
| NCT01982487 | Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial… | Phase 1 / Phase 2 | withdrawn | Nov 13, 2013 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00510224 | Sandostatin for Patients With Androgen Independent Prostate Cancer | Phase 2 | terminated | Aug 1, 2007 | University of California, San Francisco | Stopped at interim analyses phase due to lack of efficacy | Efficacy / futility |
| NCT01496534 | Phase Ib Study of Gemcitabine Plus Cisplatin or Carboplatin Plus Dovitinib in Patients… | Phase 1 | terminated | Dec 21, 2011 | Matthew Galsky | toxicity of combination of medications | Safety / toxicity |
| NCT00768742 | Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual…(FAST) | N/A | withdrawn | Oct 8, 2008 | Gynesonics | study revised and reinitiated under another protocol | Other (stated, no rule matched) |
| NCT00681148 | Botulinum Toxin Injection With Prostate Brachytherapy | Phase 2 | withdrawn | May 21, 2008 | Emory University | No funding | Funding |
| NCT00138151 | Isotretinoin, Interferon Alpha-2b, and Paclitaxel in Stage IV, Recurrent, or Persistent… | Phase 2 | terminated | Aug 30, 2005 | University of Medicine and Dentistry of New Jersey | Slow accrual and lack of study drug | Enrollment / accrual |
| NCT00945477 | Pazopanib as Second Line Therapy in Patients With Metastatic Prostate Cancer Refractory… | Phase 2 | terminated | Jul 24, 2009 | Illinois CancerCare, P.C. | Slow enrollment | Enrollment / accrual |
| NCT00831233 | Symptomatic Study Investigating Degarelix in Patients Suffering From Prostate Cancer | Phase 3 | terminated | Jan 28, 2009 | Ferring Pharmaceuticals | Poor recruitment due to rare targeted population | Enrollment / accrual |
| NCT00053833 | S0025 Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary… | Phase 2 | terminated | Feb 6, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00072540 | S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of… | Phase 2 | withdrawn | Nov 5, 2003 | SWOG Cancer Research Network | drug issues | Other (stated, no rule matched) |
| NCT01063998 | A Urinary Tumor Marker (Kidney Injury Molecule-1) for the Detection of Renal Cell… | — | terminated | Feb 5, 2010 | Jason Hafron | Preliminary data did not show expected outcomes. | Other (stated, no rule matched) |
| NCT01617174 | Observational Longitudinal Study of Pain in Men With Metastatic Castrate-Resistant… | — | withdrawn | Jun 12, 2012 | Memorial Sloan Kettering Cancer Center | not stated | Not stated |
| NCT00005075 | Ultrasound in Treating Patients With Recurrent Stage I or Stage II Prostate Cancer | Phase 3 | terminated | Feb 25, 2004 | EDAP Technomed | Withdrawn because Ablatherm devices were not available anymore at trial centers | Other (stated, no rule matched) |
| NCT01743547 | The Effects Of Yoga On Quality Of Life Among A Population Of Ovarian/ Fallopian Tube/… | N/A | terminated | Dec 6, 2012 | Northwestern University | The investigators concluded that it is not feasible due to the lack of participation and difficulty… | Enrollment / accrual |
| NCT00814892 | Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer | Phase 2 | terminated | Dec 25, 2008 | Mayo Clinic | Study was terminated due to funding issues. | Funding |
| NCT00907634 | Prospective Evaluation of Intrafractional and Interfractional Cervical Motion During… | — | withdrawn | May 22, 2009 | Emory University | Study closed by IRB because a Continuing Review and/or Close-Out have not been submitted. Study… | Other (stated, no rule matched) |
| NCT00110344 | Research Study for Patients With Metastatic Renal Cell Carcinoma | Phase 2 | terminated | May 9, 2005 | Bayer | not stated | Not stated |
| NCT01481233 | Oral Colchicine in Men With Castrate Resistant Prostate Cancer | Phase 2 | withdrawn | Nov 29, 2011 | Milton S. Hershey Medical Center | Due to funding | Funding |
| NCT00289146 | Comparison of Immune Response Following Surgical Management of Renal Tumors | — | terminated | Feb 9, 2006 | Emory University | not stated | Not stated |
| NCT00085631 | Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients… | Phase 3 | terminated | Jun 11, 2004 | Mark Dewhirst | Study was closed because of slow accrual | Enrollment / accrual |
| NCT00382330 | Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity… | N/A | withdrawn | Sep 29, 2006 | University of Medicine and Dentistry of New Jersey | not stated | Not stated |
| NCT00085527 | FR901228 in Treating Patients With Relapsed or Refractory Advanced Ovarian Epithelial… | Phase 2 | withdrawn | Jun 11, 2004 | University of Chicago | not stated | Not stated |
| NCT00203866 | Trial of G250 Peptide and IL-2 Following Surgical Resection of Locally… | Phase 2 | terminated | Sep 20, 2005 | University of Chicago | Study completed | Other (stated, no rule matched) |
| NCT01321697 | A Non-Randomized Study to Evaluate Leg Lymphatic Drainage Associated With Surgical… | — | terminated | Mar 23, 2011 | University of Arkansas | Principal Investigator Request | Investigator |
| NCT01197209 | Neoadjuvant Study of In-situ REIC/Dkk-3 in Prostate Cancer | Phase 1 | withdrawn | Sep 9, 2010 | Momotaro-Gene Inc. | Suspended due to change in development plans and investigator | Investigator |
| NCT00084370 | Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who… | N/A | withdrawn | Jun 11, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00685633 | Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate Cancer | Phase 2 | withdrawn | May 28, 2008 | Eastern Cooperative Oncology Group | not stated | Not stated |
| NCT01010334 | Comparison of Standard of Care or Treatment on Protocol | N/A | terminated | Nov 10, 2009 | New Mexico Cancer Research Alliance | PI deparature and very low (\<2%) accrual rate.(No results required) | Enrollment / accrual |
| NCT00017537 | Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer | Phase 1 | withdrawn | Jan 8, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00080639 | CA-125 in Screening Patients at High Risk for Ovarian Cancer | — | withdrawn | Apr 8, 2004 | University of Alabama at Birmingham | Terminated for administrative reasons and becuase there were no enrollments | Enrollment / accrual |
| NCT01821859 | Abraxane/Bevacizumab | Phase 2 | terminated | Apr 1, 2013 | OHSU Knight Cancer Institute | Terminated due to low enrollment | Enrollment / accrual |
| NCT00796874 | Magnetic Resonance Imaging in Detecting Cancer Progression in Patients With Early Stage… | N/A | withdrawn | Nov 24, 2008 | Roswell Park Cancer Institute | PI decided to terminate study. | Other (stated, no rule matched) |
| NCT00942838 | Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the…(WAR) | Phase 1 | withdrawn | Jul 21, 2009 | University of Utah | PI decision due to under accrual. | Enrollment / accrual |
| NCT00557830 | Randomized Study of Sorafenib Dose Escalation in Patients With Previously Untreated… | Phase 2 | terminated | Nov 14, 2007 | Accelerated Community Oncology Research Network | The study was closed to enrollment when it became clear that enrollment was too slow to complete… | Enrollment / accrual |
| NCT00084578 | Celecoxib and Rosiglitazone in Treating Patients Who Are Undergoing Cystoscopic… | N/A | withdrawn | Jun 11, 2004 | Fox Chase Cancer Center | Withdrawn due to drug toxicity | Safety / toxicity |
| NCT01899391 | Periperal Blood Lymphocytes During Prostate RT | — | withdrawn | Jul 15, 2013 | University Health Network, Toronto | Recuritment Challenges | Other (stated, no rule matched) |
| NCT00025519 | Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Recurrent… | Phase 2 | withdrawn | Jan 27, 2003 | Fox Chase Cancer Center | not stated | Not stated |
| NCT01498237 | Photoacoustic Endoscopy in Endometrial Cancer | Early Phase 1 | withdrawn | Dec 23, 2011 | Washington University School of Medicine | Need to obtain IDE prior to commencement of study | Other (stated, no rule matched) |
| NCT00003517 | Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 24 days agoSource updated Jan 29, 2014source: clinicaltrials