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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
252 stopped studies mapped to Malignant Gastric Neoplasm and descendants · 88% state a reason
Over the 252 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT03471468 | Kinetics of Microparticles Under Chemotherapy in Patients With Gastric or Pancreatic…(DOMICA) | N/A | terminated | Mar 20, 2018 | Poitiers University Hospital | Low recruitment | Enrollment / accrual |
| NCT02726399 | Phase II Study of Ramucirumab With Chemotherapy in Patients With Metastatic… | Phase 2 | terminated | Apr 1, 2016 | Memorial Sloan Kettering Cancer Center | Low accrual rate | Enrollment / accrual |
| NCT00394602 | Chemoradiation-Induced Nausea and Emesis: Quality of Life | — | terminated | Nov 1, 2006 | M.D. Anderson Cancer Center | Requested by PI during yearly Continuing Review | Other (stated, no rule matched) |
| NCT01470742 | Trial Comparing Capecitabine Plus Oxaliplatin (XELOX) and Capecitabine (X) as First-line… | Phase 3 | withdrawn | Nov 11, 2011 | Samsung Medical Center | We stop because of problems such as insurance. | Other (stated, no rule matched) |
| NCT00923052 | The Natural History of Solid Organ Cancer Stem Cells (SOCSC) | — | terminated | Jun 18, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT02318901 | Pembrolizumab and Monoclonal Antibody Therapy in Advanced Cancer(PembroMab) | Phase 1 / Phase 2 | terminated | Dec 17, 2014 | Western Regional Medical Center | PI no longer at sight. Results not collected | Other (stated, no rule matched) |
| NCT02076594 | Low-Tox Vs Eox In Patients With Locally Advanced Unresectable Or Metastatic Gastric Cancer | Phase 3 | terminated | Mar 3, 2014 | Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente | The interim analysis performed on 09 November 2018, showed the failure to achieve the primary… | Efficacy / futility |
| NCT03766607 | Trastuzumab Beyond Progression in HER2 Positive Metastatic Gastric Cancer | Phase 2 | withdrawn | Dec 6, 2018 | Korean South West Oncology Group | Competing other studies | Other (stated, no rule matched) |
| NCT01727908 | Screening for Familial Gastric Cancer in First Degree Relatives(FamGaCan) | N/A | terminated | Nov 16, 2012 | Radboud University Medical Center | guideline developed | Other (stated, no rule matched) |
| NCT00387530 | Phenylbutyrate and Valganciclovir in Treating Patients With Relapsed or Refractory… | Phase 2 | withdrawn | Oct 13, 2006 | University of California, San Diego | not stated | Not stated |
| NCT02952989 | A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors | Phase 1 | terminated | Nov 2, 2016 | Seagen Inc. | Due to overall benefit/risk profile | Other (stated, no rule matched) |
| NCT03082833 | Phase II Trial of AZD2014 in TSC1/2 Mutated or TSC1/2 Null GC Patients as Second-line… | Phase 2 | terminated | Mar 17, 2017 | Samsung Medical Center | lack of efficacy | Efficacy / futility |
| NCT02736552 | Compare S-1 for 6 Months to 1 Year as Adjuvant Chemotherapy After D2 Resection in… | Phase 3 | withdrawn | Apr 13, 2016 | Fudan University | not stated | Not stated |
| NCT03150628 | Cytoreductive Surgery and Intraperitoneal Chemotherapy for Stomach CAncer: a Feasibility…(CISCA) | Phase 2 | terminated | May 12, 2017 | Richard van Hillegersberg | Conflicting recruitment with PERISCOPE II study (NCT03348150) | Enrollment / accrual |
| NCT01365130 | Chemotherapy for Patients With Gastroesophageal Cancers Who Have Progressed After One… | Phase 2 | terminated | Jun 3, 2011 | howard safran | As of 12/12/12 study closed to enrollment because study was determined to be ineffective. | Enrollment / accrual |
| NCT03122548 | Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction… | Phase 2 | terminated | Apr 21, 2017 | Aduro Biotech, Inc. | Low enrollment and lack of clinical activity in other CRS-207 studies. | Enrollment / accrual |
| NCT00256321 | Celecoxib/Oxaliplatin/Capecitabine for Gastric/Gastroesophageal Junction Carcinoma | Phase 2 | terminated | Nov 21, 2005 | University of California, Irvine | Closed due to poor accrual | Enrollment / accrual |
| NCT02358863 | Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and…(mEGA) | N/A | terminated | Feb 9, 2015 | Georgetown University | Issues with recruitment. | Enrollment / accrual |
| NCT02216149 | Effects of S-1 and Capecitabine on Coronary Artery Blood Flow(FluoHeart) | Phase 2 | terminated | Aug 13, 2014 | Heikki Joensuu | Slow accrual | Enrollment / accrual |
| NCT00354224 | Capecitabine and Oxaliplatin in Treating Patients With Locally Advanced, Unresectable, or… | Phase 2 | terminated | Jul 20, 2006 | Medical University of South Carolina | due to low accrual | Enrollment / accrual |
| NCT02943603 | A Study of Perioperative mFOLFOX6 Plus Pembrolizumab in Patients With Potentially… | Phase 2 | withdrawn | Oct 24, 2016 | Weijing Sun, MD, FACP | No participants enrolled. PI/Sponsor left UPitt. IND withdrawn \& revised protocol submitted… | Enrollment / accrual |
| NCT02113683 | Validation of MMS Test for Cancer Monitoring(MMS-TM) | — | terminated | Apr 15, 2014 | MedInnovation GmbH | insufficient recruitment on the part of clinic; study will not resume | Enrollment / accrual |
| NCT03253185 | A Study of SC-007 in Subjects With Advanced Cancer | Phase 1 | terminated | Aug 17, 2017 | AbbVie | Benefit/Risk Imbalance | Other (stated, no rule matched) |
| NCT02150447 | The Use of Proton Pump Inhibitor on the Prevention of Gastric Cancer Bleeding | Phase 3 | terminated | May 29, 2014 | National Cancer Center, Korea | Low enroll rate | Enrollment / accrual |
| NCT02638909 | Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal… | Phase 2 | terminated | Dec 23, 2015 | Criterium, Inc. | Lack of Enrollment | Enrollment / accrual |
| NCT01813253 | Phase 3 Study of Nimotuzumab and Irinotecan as Second Line With Advanced or Recurrect… | Phase 3 | terminated | Mar 18, 2013 | Kuhnil Pharmaceutical Co., Ltd. | not stated | Not stated |
| NCT00588263 | Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish… | — | withdrawn | Jan 8, 2008 | Memorial Sloan Kettering Cancer Center | Data from MSK-IMPACT is sufficient for relevant analyses going forward | Other (stated, no rule matched) |
| NCT01683864 | Randomized Controlled Trial to Prevent Peritoneal Seeding in Gastric Cancer(HIPECStomach) | Phase 2 / Phase 3 | terminated | Sep 12, 2012 | University Hospital Tuebingen | Recruitment problems | Enrollment / accrual |
| NCT00848783 | Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed… | Phase 2 | terminated | Feb 20, 2009 | NYU Langone Health | Due to slow accrual | Enrollment / accrual |
| NCT00903396 | Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy… | Phase 2 | terminated | May 18, 2009 | Alliance for Clinical Trials in Oncology | Slow accrual | Enrollment / accrual |
| NCT01774851 | A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of… | Phase 2 | terminated | Jan 24, 2013 | Merrimack Pharmaceuticals | DSMB recommendation due to lack of efficacy. There were no safety signals. | Safety / toxicity |
| NCT01355302 | E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine… | Phase 1 / Phase 2 | terminated | May 18, 2011 | Eisai Inc. | Sites not recruiting | Enrollment / accrual |
| NCT02202759 | A Study of MLN0264 in Participants With Cancer of the Stomach or Gastroesophageal Junction | Phase 2 | terminated | Jul 29, 2014 | Millennium Pharmaceuticals, Inc. | Business Decision, No Safety or Efficacy Concerns | Safety / toxicity |
| NCT01641939 | A Study of Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal… | Phase 2 / Phase 3 | terminated | Jul 17, 2012 | Hoffmann-La Roche | not stated | Not stated |
| NCT02207959 | Gastric In Vivo Study | Phase 1 | terminated | Aug 4, 2014 | Susana Gonzalez | PI left institution | Investigator |
| NCT01814345 | Her 2 Testing in Indian Patients With Gastric Cancer | — | terminated | Mar 19, 2013 | Tata Memorial Hospital | not stated | Not stated |
| NCT02567396 | Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be… | Phase 1 | withdrawn | Oct 5, 2015 | National Cancer Institute (NCI) | Other- Protocol moved to Disapproved | Other (stated, no rule matched) |
| NCT02391038 | MLN0264 in Previously Treated Asian Participants With Advanced Gastrointestinal Carcinoma… | Phase 1 | terminated | Mar 18, 2015 | Millennium Pharmaceuticals, Inc. | The study was terminated because preliminary PK and overall clinical data demonstrated compelling… | Other (stated, no rule matched) |
| NCT01457846 | Efficacy and Safety of AZD4547 Versus Paclitaxel in Patients With Advanced Gastric or…(SHINE) | Phase 2 | terminated | Oct 24, 2011 | AstraZeneca | not stated | Not stated |
| NCT00448682 | Combination Chemotherapy as First-Line Therapy in Treating Patients With Stage IV Gastric… | Phase 2 | terminated | Mar 19, 2007 | University of Miami | not stated | Not stated |
| NCT02063412 | Nursing and Pharmacy Care Between Capecitabine and 5-Fluoruracil Regimens | — | withdrawn | Feb 14, 2014 | Vivian Wing Yan Lee | Slow recruitment pace | Enrollment / accrual |
| NCT02446379 | Use of the EnLightTM and LightPathTM Imaging Systems in Gastrointestinal Tumour Surgery(CLIO) | — | withdrawn | May 18, 2015 | Lightpoint Medical Limited | Technology licensed to third party. Sponsor did not proceed with study. | Other (stated, no rule matched) |
| NCT01433861 | Laparoscopy-assisted Proximal Gastrectomy Versus and Laparoscopy-assisted Total…(PRAPT) | Phase 3 | terminated | Sep 14, 2011 | Seoul National University Bundang Hospital | We planed to study later | Other (stated, no rule matched) |
| NCT02560740 | A Study of the Efficacy and Safety of PerOx Quench on the Prevention of Oxaliplatin… | N/A | terminated | Sep 25, 2015 | SMR Biotech Co., Ltd. | Subjects' not-well compliance due to diarrhea and softening stool after taking PerOx Quench 4… | Other (stated, no rule matched) |
| NCT01450696 | A Study of Herceptin (Trastuzumab) in Combination With Cisplatin/Capecitabine…(HELOISE) | Phase 3 | terminated | Oct 12, 2011 | Hoffmann-La Roche | futility following planned interim analysis | Efficacy / futility |
| NCT01342653 | Clinical Trial at Neoadjuvant Peritoneal and Systemic Chemotherapy Plus HIPEC in Gastric…(HIPEC) | Phase 2 | suspended | Apr 27, 2011 | Hospital General Universitario Gregorio Marañon | unable to reach planned recruitment | Enrollment / accrual |
| NCT01260194 | A Study of Herceptin (Trastuzumab) in Combination With Standard Chemotherapy in Patients… | Phase 4 | terminated | Dec 15, 2010 | Hoffmann-La Roche | not stated | Not stated |
| NCT01123473 | Epirubicin Hydrochloride, Cisplatin, and Fluorouracil or Capecitabine With or Without… | Phase 2 | terminated | May 14, 2010 | European Organisation for Research and Treatment of Cancer - EORTC | company withdrew interest | Sponsor / business decision |
| NCT01946061 | A Phase II Trial of Adjuvant Chemotherapy With S-1 Plus Oxaliplatin for Locally Advanced… | Phase 2 | terminated | Sep 19, 2013 | Yonsei University | This study was stopped because of difficulties of supplying the drug. | Other (stated, no rule matched) |
| NCT00767234 | Permission to Collect Blood Over Time for Research | — | terminated | Oct 7, 2008 | Stanford University | Accrual issues - Low Accrual | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Feb 17, 2020source: clinicaltrials