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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
826 stopped studies mapped to Malignant Female Reproductive System Neoplasm and descendants · 86% state a reason
Over the 826 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00002976 | Estrogen Replacement Therapy in Treating Women With Early-Stage Endometrial Cancer | Phase 3 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003386 | Vaccine Therapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer | Phase 2 | terminated | Apr 23, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003624 | Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine,… | Phase 2 | terminated | Jun 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00004037 | Docetaxel in Treating Patients With Recurrent or Refractory Ovarian or Primary Peritoneal… | Phase 2 | terminated | Jun 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006224 | Gemcitabine in Treating Patients With Persistent or Recurrent Cancer of the Cervix | Phase 2 | terminated | Nov 11, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006482 | Gemcitabine and Cisplatin in Treating Patients With Refractory or Recurrent Cancer of the… | Phase 2 | terminated | Oct 8, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006812 | Capecitabine in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal… | Phase 2 | terminated | Mar 17, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00016341 | Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With… | Phase 3 | terminated | Sep 9, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00023907 | Paclitaxel in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal… | Phase 2 | terminated | Jul 9, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00030472 | Liposomal Doxorubicin in Treating Patients With Persistent or Recurrent Cancer of the… | Phase 2 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00054067 | Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With… | Phase 3 | terminated | Feb 6, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00091195 | Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or… | Phase 2 | terminated | Sep 9, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT01016054 | A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With… | Phase 1 | terminated | Nov 18, 2009 | Astellas Pharma Inc | Trial was terminated to allow sponsors to evaluate the future development of the drug program | Other (stated, no rule matched) |
| NCT00005808 | Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical… | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00002796 | Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced… | Phase 1 / Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00523809 | Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid… | Phase 2 | terminated | Sep 3, 2007 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT00137358 | Radiation With Chemotherapy and a Study Drug to the Para-Aortic Nodes in Cervical Cancer | Phase 1 | withdrawn | Aug 29, 2005 | University of Alabama at Birmingham | unable to obtain funding to conduct study | Funding |
| NCT00042952 | Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage… | Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00052585 | Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent… | Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00087191 | EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or… | N/A | terminated | Jul 12, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00173407 | PTEN and IGFBP-3 Correlation in Ovarian Carcinoma Invasion | N/A | withdrawn | Sep 15, 2005 | National Taiwan University Hospital | not stated | Not stated |
| NCT00840450 | Imatinib Mesylate (Gleevec) and Paclitaxel in Recurrent Patients of Ovarian and Other… | Phase 2 | terminated | Feb 10, 2009 | NYU Langone Health | Due to slow accrual | Enrollment / accrual |
| NCT01177501 | Trial of High Dose Topotecan With Carboplatin in Patients With Relapsed Ovarian Carcinoma(ITOV04) | Phase 1 | terminated | Aug 9, 2010 | Assistance Publique - Hôpitaux de Paris | choice of the principal investigator | Investigator |
| NCT00288275 | Correlation of the Chemoresponse Assay With PFS in Patients With Recurrent Epithelial… | — | terminated | Feb 7, 2006 | Precision Therapeutics | not stated | Not stated |
| NCT00669422 | ChemoFx® PRO - A Post-Market Data Collection Study | — | terminated | Apr 30, 2008 | Precision Therapeutics | not stated | Not stated |
| NCT00460200 | Depression and Interleukin-6 Production in Patients With Ovarian Epithelial Cancer | — | withdrawn | Apr 13, 2007 | Jonsson Comprehensive Cancer Center | no patient accrual | Enrollment / accrual |
| NCT00005612 | Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating…(ETC) | Phase 1 / Phase 2 | terminated | May 3, 2004 | H. Lee Moffitt Cancer Center and Research Institute | Low accrual | Enrollment / accrual |
| NCT00006356 | Chemotherapy With or Without Surgery in Treating Patients With Recurrent Ovarian Cancer | Phase 3 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00496080 | Doppler-Guided Uterine Artery Occlusion (DUAO) Device for Fibroid Related Bleeding(DUAO) | N/A | terminated | Jul 4, 2007 | Ethicon, Inc. | Trial terminated early due to results from a similar study. | Other (stated, no rule matched) |
| NCT00516841 | A Phase 2, Single-Arm Study of Volociximab Monotherapy in Subjects With… | Phase 2 | terminated | Aug 16, 2007 | Facet Biotech | Decision to terminate recruitment based on lack of efficacy | Efficacy / futility |
| NCT01661868 | Olaparib for Patients With Recurrent BRCA Deficient Ovarian Cancer | Phase 2 | withdrawn | Aug 10, 2012 | Dana-Farber Cancer Institute | Drug not available. | Other (stated, no rule matched) |
| NCT00085384 | PEG-Interferon Alfa-2b in Treating Patients With Platinum-Resistant Ovarian Epithelial,… | Phase 1 / Phase 2 | terminated | Jun 11, 2004 | M.D. Anderson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT00897806 | Identifying Genetic Markers That Predict Response to Paclitaxel in Patients With Newly… | — | terminated | May 12, 2009 | M.D. Anderson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT01290406 | BEZ235 Trial in Patients With Advanced Endometrial Carcinoma | Phase 2 | withdrawn | Feb 7, 2011 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT00057928 | S0227 Cisplatin With Either Paclitaxel or Gemcitabine in Recurrent, Persistent, or… | Phase 3 | withdrawn | Apr 9, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00006262 | Rebeccamycin Analogue in Treating Patients With Refractory Stage III or Stage IV Ovarian… | Phase 2 | terminated | Mar 25, 2004 | Northwestern University | Unable to accrue patients to the study. | Enrollment / accrual |
| NCT01313104 | Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With… | N/A | withdrawn | Mar 11, 2011 | Northwestern University | Lack of funding | Funding |
| NCT01031056 | Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers | — | withdrawn | Dec 14, 2009 | Stanford University | Change in research focus | Other (stated, no rule matched) |
| NCT00653328 | Ph II Atrasentan + DOXIL in Recurrent Ovarian/Fallopian/Peritoneal Serous Papillary… | Phase 2 | terminated | Apr 4, 2008 | Vanderbilt-Ingram Cancer Center | Abbott (drug manufacturer) discontinued manufacture of ABT-627 | Drug supply |
| NCT00231829 | A Pilot Study of Celecoxib in Patients With Grade 2 or 3 Uterine Cancers | Phase 2 | terminated | Oct 4, 2005 | Mark H. Einstein | Due to reported toxicity of Celecoxib at high doses | Safety / toxicity |
| NCT00813254 | Cost Utility Analysis in Recurrent Ovarian Cancer | — | withdrawn | Dec 23, 2008 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00505661 | Letrozole in Patients With Ovarian Tumors | Phase 2 | terminated | Jul 23, 2007 | M.D. Anderson Cancer Center | Terminated due to slow patient accrual. | Enrollment / accrual |
| NCT00253461 | 11C Topotecan PET Imaging | Early Phase 1 | terminated | Nov 15, 2005 | Case Comprehensive Cancer Center | Drugs unavailable:unable to make radioactive topotecan | Other (stated, no rule matched) |
| NCT01212887 | Treated Blood Cells, Cyclophosphamide, Fludarabine Phosphate, and Aldesleukin in Treating… | Phase 1 | terminated | Oct 1, 2010 | Cancer Research UK | due to safety concerns and lack of efficacy | Safety / toxicity |
| NCT01096381 | Potential Biomarkers for Bevacizumab-Induced High Blood Pressure in Patients With Solid… | — | terminated | Mar 31, 2010 | Vanderbilt-Ingram Cancer Center | funding withdrawn due to fellow's departure from VICC | Funding |
| NCT00418574 | Efficacy Multicentre Trial of ImmunoTherapy Vaccination With Abagovomab to Treat Ovarian…(MIMOSA) | Phase 2 / Phase 3 | terminated | Jan 5, 2007 | Menarini Group | No benefit on primary end point (RFS); no rationale to collect survival data | Other (stated, no rule matched) |
| NCT00926107 | Study of the mTOR Inhibitor Temsirolimus (CCI-779) to Treat Ovarian Cancer With CA125… | Phase 2 | terminated | Jun 23, 2009 | Hellenic Cooperative Oncology Group | The study ended prematurely due to the low accrual rate (24% of the expected accrual rate) in the… | Enrollment / accrual |
| NCT00898781 | Study of Circulating Cancer Cells in Patients With Metastatic Breast, Ovarian, Colon, or… | — | terminated | May 12, 2009 | Mayo Clinic | Due to poor accrual | Enrollment / accrual |
| NCT00118300 | Capecitabine and Radiation Therapy in Treating Patients With Locally Advanced Cervical… | Phase 1 | withdrawn | Jul 11, 2005 | Case Comprehensive Cancer Center | Competing studies | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Apr 11, 2013source: clinicaltrials