Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
204 stopped studies mapped to Malignant Bladder Neoplasm and descendants · 91% state a reason
Over the 204 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00003452 | Antineoplastons A10 and AS2-1 In Patients With Carcinoma of the Bladder | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | slow enrollment | Enrollment / accrual |
| NCT01622660 | Gemcitabine and Pazopanib in Chemotherapy Naïve Patients With Advanced/Metastatic… | Phase 2 | terminated | Jun 19, 2012 | Memorial Sloan Kettering Cancer Center | Safety reasons | Safety / toxicity |
| NCT02027649 | Detection of K14 in Bladder Cancer With a Non Invasive Technique | — | terminated | Jan 6, 2014 | Corporacion Parc Tauli | Absence of positive results | Other (stated, no rule matched) |
| NCT01042795 | Trial of Adjuvant Sutent for Patients With High Risk Urothelial Carcinoma After… | Phase 2 | terminated | Jan 6, 2010 | University of Michigan | Study closed due to poor accrual | Enrollment / accrual |
| NCT02925533 | Ph 1B B-701 in Combination With Pembrolizumab in Metastatic Transitional Cell Carcinoma… | Phase 1 | terminated | Oct 6, 2016 | Mark Pomerantz, MD | Terminated due to safety concerns. | Safety / toxicity |
| NCT01108003 | Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer… | N/A | terminated | Apr 21, 2010 | Roswell Park Cancer Institute | low accrual | Enrollment / accrual |
| NCT00005047 | 4B951, Combination Chemotherapy in Treating Patients With Bladder Cancer | Phase 3 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | Accrual was halted on the basis of the Data and Safety Monitoring Board review of a futility… | Safety / toxicity |
| NCT01475266 | Single Immediate Instillation of EO9 After TURBT in Patients With Non-muscle-invasive… | Phase 2 / Phase 3 | terminated | Nov 21, 2011 | Nippon Kayaku Co., Ltd. | Sponsor's decision | Sponsor / business decision |
| NCT01410565 | Efficacy and Safety of Multi-Instillations of Apaziquone in Patients With Non-Muscle… | Phase 3 | terminated | Aug 5, 2011 | Spectrum Pharmaceuticals, Inc | Business reason | Sponsor / business decision |
| NCT00565227 | Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and… | Phase 1 | terminated | Nov 29, 2007 | University of Michigan Rogel Cancer Center | closed due to toxicity | Safety / toxicity |
| NCT02252393 | Urinary Diversion During Robotic Assisted Radical Cystectomy in Patients With Bladder… | N/A | withdrawn | Sep 30, 2014 | Case Comprehensive Cancer Center | waiting on surgeon training | Other (stated, no rule matched) |
| NCT02030574 | Neoadjuvant Gemcitabine and Fractionated, Weekly Cisplatin For Muscle Invasive Bladder… | Phase 2 | terminated | Jan 8, 2014 | Brown University | The study is being closed to accrual secondary to low accrual and an interest in opening up a… | Enrollment / accrual |
| NCT00022633 | S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer… | Phase 2 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | Permanently Closed Due to Poor Accrual | Enrollment / accrual |
| NCT01339000 | Improving the Immune System With Human IL-7 Vaccine in Older Subjects Who Have Had… | Phase 2 | terminated | Apr 20, 2011 | National Cancer Institute (NCI) | Company supplying drug declared bankruptcy, thus there was no drug supply. | Drug supply |
| NCT02718742 | Paclitaxel Albumin-Stabilized Nanoparticle Formulation After Cisplatin-Based Chemotherapy… | Phase 2 | withdrawn | Mar 24, 2016 | Mayo Clinic | not stated | Not stated |
| NCT01916109 | Study of Gemcitabine, Carboplatin, and Panitumumab (GCaP) as Neoadjuvant Chemotherapy in… | Phase 2 | terminated | Aug 5, 2013 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01663285 | Clinical Trial Of Neoadjuvant Chemotherapy (NAC)In Upper Tract Urothelial Carcinoma (UTUC) | Phase 2 | terminated | Aug 13, 2012 | University of Michigan Rogel Cancer Center | Low study participant enrollment. | Enrollment / accrual |
| NCT00974818 | Mitomycin C Versus Bacillus Calmette-Guerin in the Intravesical Treatment of… | Phase 3 | terminated | Sep 10, 2009 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00714948 | Gemcitabine and Split-dose Cisplatin (GC) Plus Sorafenib in Chemotherapy-naïve Patients… | Phase 2 | terminated | Jul 14, 2008 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00479089 | Iressa and Taxotere Study in Patients With Metastatic Urothelial Cancer | Phase 2 | terminated | May 25, 2007 | M.D. Anderson Cancer Center | Study halted due to drug sponsor decision to not continue. | Sponsor / business decision |
| NCT00635726 | Methotrexate, Vinblastine, Doxorubicin and Cisplatin (MVAC) Followed by Gemcitabine Plus… | Phase 2 | terminated | Mar 14, 2008 | Hellenic Oncology Research Group | Due to poor accrual | Enrollment / accrual |
| NCT00995488 | Trial of Combination ABI-007, Carboplatin, and Gemcitabine for First Line Treatment of… | Phase 2 | terminated | Oct 15, 2009 | University of Michigan Rogel Cancer Center | Terminated prematurely due to low accrual. | Enrollment / accrual |
| NCT01314664 | A Prospective Registry to Assess the Effectiveness and Local Tolerability of Intravesical… | — | terminated | Mar 14, 2011 | Endo USA Inc., a Keenova Therapeutics Company | Business decision, not safety related | Safety / toxicity |
| NCT01374789 | PURO Panitumumab in Combination With Gemcitabine/Cisplatin in Advanced Urothelial Cancer(PURO) | Phase 2 | terminated | Jun 16, 2011 | WiSP Wissenschaftlicher Service Pharma GmbH | The study was terminated due to insufficient recruitment. | Enrollment / accrual |
| NCT00785694 | Recurrence of Bladder Cancer After Transurethral Resection With Hexvix | Phase 4 | withdrawn | Nov 5, 2008 | GE Healthcare | Rejected ethics approval in UK and Holland | Other (stated, no rule matched) |
| NCT00933374 | Trial to Evaluate Paclitaxel Plus RAD001 in Urothelial Carcinoma(RAD001) | Phase 2 | terminated | Jul 7, 2009 | Heinrich-Heine University, Duesseldorf | delayed recruitment | Enrollment / accrual |
| NCT00918008 | A 12-Gene Blood-Based Signature for Detecting Metastatic Bladder Cancer | — | terminated | Jun 11, 2009 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00072137 | Neoadjuvant Intravesical Vaccine Therapy in Treating Patients With Bladder Carcinoma Who… | Phase 1 | terminated | Nov 6, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00393796 | Trial of Maintenance SUO11248 Versus Placebo Post Chemotherapy for Patients With Advanced… | Phase 2 | terminated | Oct 30, 2006 | University of Michigan Rogel Cancer Center | Low accrual | Enrollment / accrual |
| NCT00384891 | Hyperthermia Treatment in Conjunction With Mitomycin C Versus Bacillus Calmette-Guérin… | Phase 3 | terminated | Oct 6, 2006 | Medical Enterprises Europe B.V. | slow accrual | Enrollment / accrual |
| NCT01284205 | First Line Comparative Study of EN3348 (MCC) vs BCG in NMIBC | Phase 3 | withdrawn | Jan 26, 2011 | Bioniche Life Sciences Inc. | This indication is not being pursued at this point in time. | Other (stated, no rule matched) |
| NCT01688414 | Imaging During Surgery in Diagnosing Patients With Prostate, Bladder, or Kidney Cancer | N/A | withdrawn | Sep 19, 2012 | Stanford University | PI left Stanford | Investigator |
| NCT00112905 | Sorafenib in Treating Patients With Regional or Metastatic Cancer of the Urothelium | Phase 2 | terminated | Jun 3, 2005 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00802633 | Radical Cystectomy: Can We Improve Our Surgical Technique With the Ligasure Impact… | N/A | terminated | Dec 5, 2008 | Vanderbilt University | Enrollment was stopped after eighty patients were enrolled. | Enrollment / accrual |
| NCT01639521 | Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine,… | Phase 2 | withdrawn | Jul 12, 2012 | University of Southern California | Lack of funding | Funding |
| NCT00014287 | Gemcitabine in Treating Patients With Recurrent or Refractory Bladder Cancer | Phase 1 | withdrawn | Jan 7, 2004 | University of Pittsburgh | not stated | Not stated |
| NCT01496534 | Phase Ib Study of Gemcitabine Plus Cisplatin or Carboplatin Plus Dovitinib in Patients… | Phase 1 | terminated | Dec 21, 2011 | Matthew Galsky | toxicity of combination of medications | Safety / toxicity |
| NCT01010334 | Comparison of Standard of Care or Treatment on Protocol | N/A | terminated | Nov 10, 2009 | New Mexico Cancer Research Alliance | PI deparature and very low (\<2%) accrual rate.(No results required) | Enrollment / accrual |
| NCT00084578 | Celecoxib and Rosiglitazone in Treating Patients Who Are Undergoing Cystoscopic… | N/A | withdrawn | Jun 11, 2004 | Fox Chase Cancer Center | Withdrawn due to drug toxicity | Safety / toxicity |
| NCT00516750 | Gene Expression Profiling in Patients With Invasive Bladder Cancer Receiving… | Phase 2 | terminated | Aug 15, 2007 | Kyoto University | Withdrawn due to lack of enrollment. | Enrollment / accrual |
| NCT01282333 | Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced… | Phase 1 | terminated | Jan 25, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00004856 | Trastuzumab in Treating Patients With Previously Treated, Locally Advanced, or Metastatic… | Phase 2 | terminated | Sep 30, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01700010 | Trial of Lapatinib and Weekly Paclitaxel for Advanced Urothelial Cancer | Phase 2 | withdrawn | Oct 4, 2012 | University of Michigan Rogel Cancer Center | Funding issues. | Funding |
| NCT01245660 | A Phase 0 of Neoadjuvant Lapatinib in Infiltrative Bladder Carcinoma Before Cystectomy(LAPAINBLAD) | Early Phase 1 | terminated | Nov 22, 2010 | University Hospital, Bordeaux | The rythm of enrollment was not compatible with the objective of recruitement in the research. | Enrollment / accrual |
| NCT00087295 | S0400, FR901228 in Treating Patients With Advanced Cancer of the Urothelium | Phase 2 | terminated | Jul 12, 2004 | SWOG Cancer Research Network | Permanently Closed Due to Poor Accrual | Enrollment / accrual |
| NCT01551407 | Detection of Bladder Tumors After 30 Min Instillation of Hexvix | Phase 2 | terminated | Mar 12, 2012 | Photocure | slow inclusion rate | Other (stated, no rule matched) |
| NCT00042887 | Chemotherapy With or Without Surgery in Treating Patients With Bladder Cancer | Phase 3 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00147238 | A Validation Study of MR Lymphangiography Using SPIO, a New Lymphotropic… | N/A | terminated | Sep 7, 2005 | M.D. Anderson Cancer Center | Terminated at request of sponsor. | Other (stated, no rule matched) |
| NCT00237575 | Randomized Phase III Trial of Leukine® vs Neupogen® in Patients Receiving Cisplatin &… | Phase 3 | terminated | Oct 12, 2005 | University of Kentucky | not stated | Not stated |
| NCT00003824 | S9809, Ciprofloxacin Compared With Cephalexin in Treating Patients With Bladder Cancer | Phase 3 | terminated | Apr 14, 2004 | SWOG Cancer Research Network | Permanently Closed Due to Poor Accrual | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Sep 28, 2017source: clinicaltrials