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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
173 stopped studies mapped to Malignant Biliary Tract Neoplasm and descendants · 92% state a reason
Over the 173 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00907413 | Photodynamic Therapy (PDT) Trial for Palliation of Cholangiocarcinoma(PDT) | Phase 3 | terminated | May 22, 2009 | Weill Medical College of Cornell University | PI relocated and reopened trial in new university | Other (stated, no rule matched) |
| NCT01439685 | Comparison of Biliary Stenting Alone vs. Stenting With Photodynamic Therapy (PDT) During…(PDT) | — | withdrawn | Sep 23, 2011 | Weill Medical College of Cornell University | A single cohort, alternative trial was started. | Other (stated, no rule matched) |
| NCT01434459 | Study of Gemcitabine With TheraSphere® (Yttrium-90)in Patients With Hepatic Tumors of… | Phase 1 | terminated | Sep 15, 2011 | Emory University | PI moved to different institution | Other (stated, no rule matched) |
| NCT00881504 | A Study of FOLFOX6 With Bevacizumab for Biliary System Carcinoma | Phase 2 | terminated | Apr 15, 2009 | Georgetown University | It was not possible to get insurance companies to cover bevacizumab. | Other (stated, no rule matched) |
| NCT01859182 | Selumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced… | Phase 2 | withdrawn | May 21, 2013 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01171755 | Phase II Study of Gemcitabine and TS-1 in Biliary Trat Cancer(GetBil) | Phase 2 | terminated | Jul 28, 2010 | Samsung Medical Center | The objective response rate by more than two people are confirmed. | Other (stated, no rule matched) |
| NCT00023946 | BMS-247550 in Treating Patients With Liver or Gallbladder Cancer | Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00708877 | Liver Transplantation for Cholangiocarcinoma | N/A | terminated | Jul 2, 2008 | University of Utah | study procedures have become standard of care as patients seeking Model for End-Stage Liver Disease… | Other (stated, no rule matched) |
| NCT00896467 | Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer… | — | terminated | May 11, 2009 | Centre Oscar Lambret | not stated | Not stated |
| NCT01282333 | Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced… | Phase 1 | terminated | Jan 25, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01859169 | Safety and Efficiency of Photodynamic Therapy for Blie Duct Carcinoma | — | suspended | May 21, 2013 | li xiong | Modifying the clinnicaltrials | Other (stated, no rule matched) |
| NCT00012246 | Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract | Phase 2 | terminated | Jan 27, 2003 | The University of Texas Medical Branch, Galveston | Administratively Terminated | Other (stated, no rule matched) |
| NCT00253617 | Stent Placement With or Without Photodynamic Therapy Using Porfimer Sodium as Palliative… | Phase 3 | withdrawn | Nov 15, 2005 | Jonsson Comprehensive Cancer Center | not stated | Not stated |
| NCT00959946 | Study Of Bosutinib With Capecitabine In Solid Tumors And Locally Advanced Or Metastatic… | Phase 1 / Phase 2 | terminated | Aug 17, 2009 | Pfizer | not stated | Not stated |
| NCT00087191 | EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or… | N/A | terminated | Jul 12, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00387348 | Escitalopram in Treating Depression in Patients With Advanced Lung or Gastrointestinal… | Phase 3 | terminated | Oct 13, 2006 | Massachusetts General Hospital | DSMB stopped study because placebo arm had more adverse events | Safety / toxicity |
| NCT00713687 | Gemcitabine/Oxaliplatin and Photodynamic Therapy in Cholangiocarcinoma(GemOx-PDT) | Phase 2 | withdrawn | Jul 11, 2008 | Technical University of Munich | recruiting failed | Enrollment / accrual |
| NCT00426829 | Proton Therapy and Bevacizumab for Primary Liver Tumors | Phase 1 | terminated | Jan 25, 2007 | M.D. Anderson Cancer Center | Low Accural | Other (stated, no rule matched) |
| NCT00030511 | Radiation Therapy and Fluorouracil Before Surgery in Treating Patients With Primary or… | Phase 2 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT01096745 | Randomized Trial of Gemcitabine/Cisplatin Versus S-1/Cisplatin in Advanced Biliary Cancer | Phase 2 | terminated | Mar 31, 2010 | Gyeongsang National University Hospital | Planning for randomized phase III trial for this issue. | Other (stated, no rule matched) |
| NCT00005997 | Rebeccamycin Analogue in Treating Patients With Advanced Liver and/or Biliary Cancer | Phase 2 | terminated | Jan 27, 2003 | Case Comprehensive Cancer Center | slow accrual for Cohort II | Enrollment / accrual |
| NCT00540735 | Efficiency Evaluation of Photodynamic Therapy With Photofrin® on Unresectable Type III or…(CK/PDT) | Phase 3 | terminated | Oct 8, 2007 | University Hospital, Angers | Big difficulties to enroll patients | Enrollment / accrual |
| NCT00090025 | XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary… | Phase 3 | terminated | Aug 23, 2004 | Helsinn Healthcare SA | Futility reasons after Independent Data Monitoring Committee interim analysis | Efficacy / futility |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Jun 3, 2015source: clinicaltrials