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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,738 stopped studies mapped to Lymphoma and descendants · 89% state a reason
Over the 1,738 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00474188 | A Study to Evaluate Lenalidomide Combined With Dexamethasone in Relapsed or Refractory… | Phase 2 | terminated | May 16, 2007 | Celgene Corporation | Business decision | Sponsor / business decision |
| NCT00306332 | T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell Transplantation | Phase 3 | terminated | Mar 23, 2006 | Radboud University Medical Center | Interim analysis has shown that the objectives of this study can not be reached | Efficacy / futility |
| NCT00955292 | Dose-escalation Study of Quarfloxin in Patients With Advanced Solid Tumors or Lymphomas | Phase 1 | terminated | Aug 10, 2009 | Cylene Pharmaceuticals | Modified dose schedule presented no advantage over previously studied schedule | Other (stated, no rule matched) |
| NCT00441025 | The Effectiveness of Alemtuzumab Combination With CHOP to Treat Patients Newly Diagnosed… | Phase 2 | terminated | Feb 27, 2007 | Mahidol University | a lack of a potential patient. | Other (stated, no rule matched) |
| NCT00209014 | Phase II Trial of Thalidomide in Refractory/Relapsed Diffuse Large B-Cell Lymphoma and… | Phase 2 | terminated | Sep 21, 2005 | Emory University | Celgene unable to continue funds. | Funding |
| NCT00547404 | Phase I Study for Safety and Efficacy of P276-00 in Subjects With Myeloma | Phase 1 | withdrawn | Oct 22, 2007 | Piramal Enterprises Limited | Not to expose the patients to subtherapeutic dose | Other (stated, no rule matched) |
| NCT00083564 | Study Comparing STR (Skeletal Targeted Radiotherapy) Plus Melphalan to Melphalan Alone,… | Phase 3 | terminated | May 28, 2004 | Poniard Pharmaceuticals | For business reasons | Sponsor / business decision |
| NCT00039754 | A Trial of Skeletal Targeted Radiotherapy Using Holmium-166-DOTMP in Patients With… | Phase 1 / Phase 2 | terminated | Jun 11, 2002 | Poniard Pharmaceuticals | business reasons | Sponsor / business decision |
| NCT00352742 | A Study of ATN-224 and Bortezomib in Patients With Multiple Myeloma | Phase 1 / Phase 2 | terminated | Jul 17, 2006 | Attenuon | not stated | Not stated |
| NCT00538096 | A Phase I Study to Evaluate Safety, Tolerability in Adults With Lymphoma | Phase 1 | withdrawn | Oct 2, 2007 | MedImmune LLC | Replacing this trial with a new trial. | Other (stated, no rule matched) |
| NCT00147485 | A Phase 1 Study Of An Intravenously Administered Cyclin-Dependent Kinase Inhibitor In… | Phase 1 | terminated | Sep 7, 2005 | Pfizer | See Detailed Description | Other (stated, no rule matched) |
| NCT00148018 | Study of Bortezomib (Velcade) in Combination With Dexamethasone to Treat Patients With… | Phase 2 | terminated | Sep 7, 2005 | University of Cologne | not stated | Not stated |
| NCT00200668 | Comparison Between FDG-PET and MRI for the Assessment of Response to Intensive… | N/A | terminated | Sep 20, 2005 | Nantes University Hospital | not stated | Not stated |
| NCT00234481 | Safety Study of XL844 in Subjects With Chronic Lymphocytic Leukemia | Phase 1 | terminated | Oct 7, 2005 | Exelixis | Study closed due to slow enrollment | Enrollment / accrual |
| NCT00363610 | A Study Evaluating IV Oncaspar® and IV Gemzar® in the Treatment of Solid Tumors and… | Phase 1 | terminated | Aug 15, 2006 | Enzon Pharmaceuticals, Inc. | No recommended Phase II dose was determined. | Other (stated, no rule matched) |
| NCT00250861 | Trial of Outpatient Immunotherapy With Rituximab and Aldesleukin (IL-2) vs. Rituximab… | Phase 2 | terminated | Nov 8, 2005 | US Oncology Research | Study terminated due to lack of enrollment. | Enrollment / accrual |
| NCT00644306 | Comparison of Melphalan-Prednisone (MP) to MP Plus Thalidomide in the Treatment of Newly…(IFM 01/01) | Phase 3 | terminated | Mar 26, 2008 | Central Hospital, Nancy, France | survival advantage demonstrated | Other (stated, no rule matched) |
| NCT00510471 | Personalized Active Immunotherapy (Vaccine Therapy) and Sargramostim Given After Standard… | Phase 2 | terminated | Aug 2, 2007 | Genitope Corporation | not stated | Not stated |
| NCT00630903 | PUVA Versus PUVA + IFN Alpha 2a in Mycosis Fungoides(MF99) | Phase 4 | terminated | Mar 7, 2008 | Madrilenian Group of Cutaneous Lymphomas | Insufficient accrual | Enrollment / accrual |
| NCT00265928 | Bortezomib and Rituximab in Treating Patients With Relapsed or Refractory B-Cell… | Phase 2 | terminated | Dec 15, 2005 | University of Virginia | Withdrawn for poor accrual | Enrollment / accrual |
| NCT00141700 | Study of Rituximab Plus High-Dose Chemotherapy Poor Prognosis Non-Hodgkin's Lymphoma | Phase 2 | terminated | Sep 1, 2005 | University of Michigan Rogel Cancer Center | enrollment completed | Enrollment / accrual |
| NCT00077493 | BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute… | Phase 1 | suspended | Feb 12, 2004 | MedImmune LLC | protocol development and Amended protocol revision | Other (stated, no rule matched) |
| NCT00367497 | Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and… | Phase 2 | terminated | Aug 23, 2006 | Keio University | The stopping rule was applied because of low response rates. | Other (stated, no rule matched) |
| NCT00120198 | Pegylated Liposomal Doxorubicin Containing Chemotherapy in the Treatment of Older… | Phase 2 | terminated | Jul 15, 2005 | Geriatric Oncology Consortium | slow accrual | Enrollment / accrual |
| NCT00057447 | Safety of Interferon Gamma-1b With Rituximab in Non-Hodgkin's Lymphoma Patients | Phase 1 / Phase 2 | terminated | Apr 3, 2003 | InterMune | administrative reasons | Other (stated, no rule matched) |
| NCT00100347 | Safety/Tolerance Study of PPI-2458 in Subjects With Non-Hodgkin's Lymphoma and Solid… | Phase 1 | terminated | Dec 30, 2004 | PRAECIS Pharmaceuticals Inc. | terminated due to corporate transaction. | Other (stated, no rule matched) |
| NCT00496743 | Study of Low-Dose Total Skin Electron Beam Therapy in Mycosis Fungoides | N/A | terminated | Jul 4, 2007 | Bispebjerg Hospital | The study was discontinued after the first 10 patients because of discouraging results. | Other (stated, no rule matched) |
| NCT00105313 | Study to Evaluate MEDI-507 in Patients With CD2-Positive Lymphoma/Leukemia | Phase 1 | terminated | Mar 14, 2005 | MedImmune LLC | After review of safety events and have decided that further dose escalation of MEDI-507 as a single… | Safety / toxicity |
| NCT00143884 | Study of Low Intensity Conditioning and Immunotherapy for High-Risk Cancers of the Blood | Phase 2 | terminated | Sep 2, 2005 | University of Michigan Rogel Cancer Center | not stated | Not stated |
| NCT00133302 | Study of Standard CHOP Versus Biweekly CHOP in Aggressive Non-Hodgkin's Lymphoma… | Phase 3 | terminated | Aug 23, 2005 | Japan Clinical Oncology Group | not stated | Not stated |
| NCT00057343 | Safety and Efficacy of Zevalin in the Treatment of Non-Hodgkin's Lymphoma | Phase 3 | terminated | Apr 1, 2003 | Biogen | not stated | Not stated |
| NCT00180895 | Rituximab in Children and Adolescents With Relapsed and Refractory B-Cell NHL/L3ALL | Phase 2 | terminated | Sep 16, 2005 | Gustave Roussy, Cancer Campus, Grand Paris | not stated | Not stated |
| NCT00337506 | Velcade Combined With High-Dose Dexamethasone in Patients With Newly Diagnosed Multiple… | Phase 2 | terminated | Jun 16, 2006 | Nantes University Hospital | not stated | Not stated |
| NCT00100737 | Comparing Interleukin-2 (IL-2) Combined With Rituximab (Rituxan) to Rituximab Alone in… | Phase 2 | terminated | Jan 7, 2005 | Chiron Corporation | not stated | Not stated |
| NCT00083473 | A Pilot Study of Pivanex in Patients With Chronic Lymphocytic Leukemia | Phase 2 | terminated | May 26, 2004 | Titan Pharmaceuticals | not stated | Not stated |
| NCT00126243 | Efficacy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (CHOP)… | Phase 2 | terminated | Aug 3, 2005 | French National Agency for Research on AIDS and Viral Hepatitis | not stated | Not stated |
| NCT00023166 | Phase I Study of PEG-Paclitaxel In Patients With Advanced Solid Tumors & Lymphomas | Phase 1 | terminated | Aug 27, 2001 | Enzon Pharmaceuticals, Inc. | not stated | Not stated |
| NCT00043459 | Study of T900607-Sodium in Previously Treated Patients With Non-Hodgkin's Lymphoma. | Phase 2 | terminated | Aug 12, 2002 | Tularik | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Sep 2, 2009source: clinicaltrials