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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,739 stopped studies mapped to Lymphoma and descendants · 89% state a reason
Over the 1,739 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00060294 | Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Waldenstrom's… | Phase 1 | terminated | May 7, 2003 | Jonsson Comprehensive Cancer Center | no accrual | Enrollment / accrual |
| NCT00081068 | Alemtuzumab in Treating Patients With Waldenstrom's Macroglobulinemia | Phase 2 | withdrawn | Apr 8, 2004 | Jonsson Comprehensive Cancer Center | not stated | Not stated |
| NCT00301795 | Rituximab and Oblimersen in Treating Patients With Stage II, Stage III, or Stage IV… | Phase 2 | terminated | Mar 13, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00902525 | Zevalin Twice in Aggressive Non-Hodgkin Lymphoma | Phase 2 | terminated | May 15, 2009 | Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie | After enrolling 25 patients an interim analysis was done.The study was discontinued in the absence… | Efficacy / futility |
| NCT00727207 | Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With… | Phase 2 | terminated | Aug 1, 2008 | Technical University of Munich | Lack of participations (8 of 25) | Other (stated, no rule matched) |
| NCT00850499 | Phase 2 Study of VELCADE With Fludarabine in Comparison to Rituximab With Fludarabine in… | Phase 2 | terminated | Feb 25, 2009 | Millennium Pharmaceuticals, Inc. | not stated | Not stated |
| NCT00005852 | Bone Marrow Transplantation in Treating Patients With Severe Aplastic Anemia or Rejection… | Phase 2 | terminated | Jul 26, 2004 | H. Lee Moffitt Cancer Center and Research Institute | low accrual | Enrollment / accrual |
| NCT00541424 | Combined CT Colonography and PET Imaging in Mantle Cell Lymphoma | — | withdrawn | Oct 10, 2007 | M.D. Anderson Cancer Center | No study recruitment due to time constraints and lack of support. | Enrollment / accrual |
| NCT00361621 | Ph II CHOP+Velcade in Mediastinal LBCL | Phase 2 | terminated | Aug 8, 2006 | Dana-Farber Cancer Institute | Closed due to slow accrual | Enrollment / accrual |
| NCT00636155 | EL625 in Persistent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma | Phase 2 | terminated | Mar 14, 2008 | David Rizzieri | funding | Funding |
| NCT00699296 | Study of Oral LBH589 in Patients With Cutaneous T-cell Lymphoma and Adult T-cell… | Phase 2 | terminated | Jun 17, 2008 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT01568632 | Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma | Phase 1 | withdrawn | Apr 2, 2012 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01649622 | Bendamustine in Acute Lymphoblastic Leukemia/Lymphoma (ALL) | Phase 2 | withdrawn | Jul 25, 2012 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00058773 | Giving Gene Marked EBV Specific T-Cells to Patients Receiving a BMT for Relapsed…(ANGELA) | Phase 1 | terminated | Apr 15, 2003 | Baylor College of Medicine | not stated | Not stated |
| NCT00742495 | Pharmacokinetic Study of Forodesine in Children With Relapsed or Refractory T-cell or…(BCX1777-108) | Phase 1 / Phase 2 | terminated | Aug 27, 2008 | Mundipharma Research Limited | Slow Recruitment | Enrollment / accrual |
| NCT00972101 | Infusion of Expanded Cord Blood T Cells | Phase 1 | withdrawn | Sep 4, 2009 | M.D. Anderson Cancer Center | Development of other studies led to termination without recruitment. | Enrollment / accrual |
| NCT00301912 | Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With… | Phase 2 | withdrawn | Mar 13, 2006 | University of California, San Francisco | Withdrawn because study never opened to accrual | Enrollment / accrual |
| NCT01300793 | Study of Standard-Dose Rituximab, Ifosfamide, Carboplatin and Etoposide(V-RICE) | Phase 1 | terminated | Feb 23, 2011 | University of California, San Francisco | closed for low accrual and no data is available. | Enrollment / accrual |
| NCT00060385 | Combination Chemotherapy With or Without Etoposide in Treating Older Patients With… | Phase 2 / Phase 3 | terminated | May 7, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00062231 | Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in… | N/A | terminated | Jun 6, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00969085 | Trial of Curcumin in Cutaneous T-cell Lymphoma Patients | Phase 2 | withdrawn | Aug 31, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT01269203 | Efficacy of NF-kB Inhibition for Reducing Symptoms During Maintenance Therapy in Multiple… | Phase 2 | withdrawn | Jan 4, 2011 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00793650 | Combination High Dose Melphalan and Autologous Peripheral Blood Stem Cell (PBSC)… | Phase 1 / Phase 2 | terminated | Nov 19, 2008 | Emory University | not stated | Not stated |
| NCT00968331 | Study of Lenalidomide(Revlimid) Plus Rituximab (Revlirit Regimen) in Elderly Patients… | Phase 2 | terminated | Aug 31, 2009 | University of Bologna | The EC withdrawn the approval becuase of possible conflicts of interests between our Institute and… | Other (stated, no rule matched) |
| NCT01036399 | Study of Lenalidomide (Revlimid) in Patients With Relapsed/Refractory Peripheral T-cell… | Phase 2 | terminated | Dec 21, 2009 | University of Bologna | The EC withdrawn the approval becuase of possible conflicts of interests between our Institute and… | Other (stated, no rule matched) |
| NCT00038818 | CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell… | N/A | terminated | Jun 7, 2002 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT00242827 | Efficacy and Safety of Oral CEP-701 for the Treatment of Patients With Advanced Multiple… | Phase 2 | terminated | Oct 21, 2005 | Cephalon | not stated | Not stated |
| NCT00726869 | A Phase 1/2, Multi-center, Open-label, Dose-escalation Study of Elotuzumab(Humanized… | Phase 1 | terminated | Aug 1, 2008 | Abbott | Enrollment has been halted | Enrollment / accrual |
| NCT00453193 | Alemtuzumab and Pentostatin In T-cell Neoplasms | Phase 2 | terminated | Mar 28, 2007 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT00810576 | Combination of Vorinostat and Bortezomib in Relapsed or Refractory T-Cell Non-Hodgkin's… | Phase 2 | terminated | Dec 18, 2008 | M.D. Anderson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT00074763 | Comparing Fresh Random Platelets and Autologous Cryopreserved Thrombosol Treated… | Phase 3 | terminated | Dec 23, 2003 | M.D. Anderson Cancer Center | Terminated due to low recruitment. | Enrollment / accrual |
| NCT00939172 | TTP607 in Refractory Solid Malignancies | Phase 1 | withdrawn | Jul 14, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT01103388 | Rituximab Maintenance After Autologous Transplantation | Phase 3 | terminated | Apr 14, 2010 | M.D. Anderson Cancer Center | Closed early due to slow patient accrual and sponsor's withdrawal of support. | Enrollment / accrual |
| NCT00843050 | A Phase II Study to Evaluate Efficacy and Safety of P276-00 in Relapsed and/or Refractory… | Phase 2 | terminated | Feb 13, 2009 | Piramal Enterprises Limited | The study was terminated based on interim results and all subjects were off study at that time. No… | Safety / toxicity |
| NCT00127881 | Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sezary Syndrome | Phase 3 | terminated | Aug 9, 2005 | Emergent Product Development Seattle LLC | New sponsor, other treatments available | Other (stated, no rule matched) |
| NCT01139359 | Safety Study of Darinaparsin in Combination With Cyclophosphamide, Doxorubicin,… | Phase 1 | withdrawn | Jun 8, 2010 | Alaunos Therapeutics | Study enrollment was withdrawn as it is no longer the sponsor's intention to study this indication… | Enrollment / accrual |
| NCT00014326 | Involved-Field Radiation Therapy in Treating Patients With Previously Untreated Stage I… | Phase 3 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00368121 | EMMA-1 (Erbitux for Multiple Myeloma)(EMMA-1) | Phase 2 | terminated | Aug 24, 2006 | Prof. Dr. Andreas Engert | Lack of recruitable patients | Enrollment / accrual |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT00003152 | Chemotherapy Plus Interferon Alfa Alone or With Radiation Therapy and Peripheral Stem… | Phase 3 | terminated | Aug 2, 2004 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00208975 | Phase II Study of Fludarabine and Mitoxantrone, Followed by GM-CSF(Granulocyte-macrophage… | Phase 2 | terminated | Sep 21, 2005 | Emory University | slow accrual | Enrollment / accrual |
| NCT00886496 | Recombinant Human Mannose-Binding Lectin (MBL) in Treating Young Patients With MBL… | Phase 1 | withdrawn | Apr 23, 2009 | Enzon Pharmaceuticals, Inc. | No participants enrolled. IND withdrawn. | Enrollment / accrual |
| NCT00005595 | Arsenic Trioxide in Treating Patients With Relapsed or Refractory Hodgkin's Disease | Phase 2 | terminated | Mar 4, 2004 | Northwestern University | Unable to accrue subjects in a timely fashion. | Enrollment / accrual |
| NCT00004106 | Temozolomide in Treating Patients With Mycosis Fungoides or Sezary Syndrome | Phase 2 | terminated | Jan 27, 2003 | Northwestern University | Per Data Monitoring Committee given the poor/inadequate accrual. | Enrollment / accrual |
| NCT00005788 | Interleukin-2 in Treating Patients With Mycosis Fungoides or Sezary Syndrome | Phase 2 | terminated | Jan 27, 2003 | Northwestern University | Low/inadequate rate of accrual. | Enrollment / accrual |
| NCT00005787 | Peripheral Stem Cell Transplantation to Prevent Neutropenia in Patients Receiving… | Phase 1 | terminated | Jan 27, 2003 | Northwestern University | Per PI due to poor/inadequate accrual. | Enrollment / accrual |
| NCT00253552 | G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic Disorders | N/A | terminated | Nov 15, 2005 | OHSU Knight Cancer Institute | Terminated at request of PI as study was outdated. | Other (stated, no rule matched) |
| NCT00383097 | Lmp1 and Lmp2 Specific CTLs Following Cd45 Antibody for Relapsed Ebv-Positive Hodgkin's…(ALDI) | Phase 1 | terminated | Oct 2, 2006 | Baylor College of Medicine | The trial was terminated in 2010 due to lack of enrollment. | Enrollment / accrual |
| NCT00734773 | Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL | Early Phase 1 | withdrawn | Aug 14, 2008 | Northwestern University | Lack of funding | Funding |
| NCT01492881 | Study of Vorinostat With Doxil and Bortezomib for Patients With Relapsed/Refractory… | Phase 2 | withdrawn | Dec 15, 2011 | UNC Lineberger Comprehensive Cancer Center | Doxil is currently unavailable | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jan 8, 2013source: clinicaltrials