Terminated, withdrawn and suspended trials

clinicaltrialsObservedShowing 1,101–1,150 of 1,440 studies, most recently updated first

NCT	Title	Phase	Status	First posted	Lead sponsor	Why stopped (as posted)	Category
NCT02345772	Neoadjuvant Hormonal Therapy Combined With Chemoimmunotherapy(Neohttp)	Phase 1 / Phase 2	terminated	Jan 26, 2015	Western Regional Medical Center	PI no longer at site. Data was not collected	Other (stated, no rule matched)
NCT02496832	A Study of Hypoxia Imaging in Advanced Pancreatic Cancer Patients Being Treated With…	N/A	withdrawn	Jul 14, 2015	University Health Network, Toronto	Study was never initiated	Other (stated, no rule matched)
NCT00878215	Clinical Application of Image-Guided Liver Surgery	Phase 2	terminated	Apr 8, 2009	Washington University School of Medicine	The image-guidance system became commercially available	Other (stated, no rule matched)
NCT02392377	Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal…	Phase 2	terminated	Mar 19, 2015	Case Comprehensive Cancer Center	Slow accrual	Enrollment / accrual
NCT01934179	Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal…	—	terminated	Sep 4, 2013	Fox Chase Cancer Center	Low Accrual Rate	Enrollment / accrual
NCT02338570	Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With…(ORCHIDEE)	Phase 4	terminated	Jan 14, 2015	Mario Negri Institute for Pharmacological Research	Stopped on November 16th 2016, because of recruitment failure.	Enrollment / accrual
NCT01956864	Study of High-Dose Oral Vitamin D for the Prevention of Liver Cancer	Phase 1	withdrawn	Oct 8, 2013	Johns Hopkins University	PI transferred from Georgetown to Johns Hopkins University. No participants enrolled at either…	Enrollment / accrual
NCT02407561	Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein…	—	terminated	Apr 3, 2015	Castle Biosciences Incorporated	Futility - unable to secure sites and samples for participation	Efficacy / futility
NCT02494388	Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions(CINE-Cyst)	—	terminated	Jul 10, 2015	University of Medicine and Pharmacy Craiova	not stated	Not stated
NCT02908165	Randomized Phase II Trial of Chemoembolization and Sorafenib	Phase 2	withdrawn	Sep 20, 2016	Yale University	A future study will be taking place using the same patient population.	Other (stated, no rule matched)
NCT00848783	Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed…	Phase 2	terminated	Feb 20, 2009	NYU Langone Health	Due to slow accrual	Enrollment / accrual
NCT01012362	Study of Pazopanib and Ixabepilone in Patients With Solid Tumors	Phase 1	terminated	Nov 13, 2009	Masonic Cancer Center, University of Minnesota	PI left institution.	Investigator
NCT01372618	Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor	Phase 1 / Phase 2	terminated	Jun 14, 2011	NYU Langone Health	PI has passed away. Requested by department to terminate study.	Other (stated, no rule matched)
NCT01762592	REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With…	Phase 3	withdrawn	Jan 7, 2013	Heidelberg Pharma AG	new sponsor	Other (stated, no rule matched)
NCT03307941	Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced…(ARTEMIS-Eso)	Phase 1 / Phase 2	withdrawn	Oct 12, 2017	Jules Bordet Institute	Suspended collaboration with the company providing the study drug	Sponsor / business decision
NCT02406508	Sequential Melphalan for Use With Hepatic Delivery System Treatment Followed by Sorafenib…	Phase 2	withdrawn	Apr 2, 2015	Delcath Systems Inc.	No enrollment in the study	Enrollment / accrual
NCT01200810	Bicalutamide and RO4929097 in Treating Patients With Previously Treated Prostate Cancer	Phase 2	terminated	Sep 14, 2010	National Cancer Institute (NCI)	Drug was no longer available	Other (stated, no rule matched)
NCT02473094	Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal…(NEOMETRE)	Phase 2	terminated	Jun 16, 2015	University of Campinas, Brazil	Slow Accrual	Enrollment / accrual
NCT02122003	Second Line Sorafenib After Pazopanib in Patients With RCC(SOAP)	Phase 2	terminated	Apr 24, 2014	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	availability of new and more promising therapeutic agents than expected in the experimentation in…	Other (stated, no rule matched)
NCT02549755	11C-acetate for Treatment Response After Radiotherapy for HCC	Phase 2	terminated	Sep 15, 2015	Justin Sims	Poor enrollment	Enrollment / accrual
NCT00003530	Antineoplaston Therapy in Treating Patients With Primary Liver Cancer	Phase 2	terminated	Jan 27, 2003	Burzynski Research Institute	Slow accrual	Enrollment / accrual
NCT00158886	Oral Topotecan As A Radiosensitizing Agent In Rectal Cancer	Phase 1	terminated	Sep 12, 2005	GlaxoSmithKline	not stated	Not stated
NCT02138578	Trial Comparing Stereotactic Body Radiation Therapy to Radiofrequency Ablation for Renal…	N/A	terminated	May 14, 2014	University of Michigan Rogel Cancer Center	Due to changes in scanning procedure, and infeasible biopsy and baseline imaging, the trial closed…	Enrollment / accrual
NCT02958163	Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR)(HepSTAR)	Phase 2	terminated	Nov 8, 2016	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	lack of recruitment	Enrollment / accrual
NCT00070317	Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1…	N/A	terminated	Oct 7, 2003	Gynecologic Oncology Group	not stated	Not stated
NCT01492192	RGD-PET-CT in Cancer Angiogenesis	Phase 2	terminated	Dec 14, 2011	Oxford University Hospitals NHS Trust	not stated	Not stated
NCT01606124	Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer	Phase 2	terminated	May 25, 2012	Mayo Clinic	pending expiration of the supply of study agent.	Drug supply
NCT02564549	MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk…	N/A	terminated	Sep 30, 2015	Virginia Commonwealth University	Study halted prematurely and will not resume	Other (stated, no rule matched)
NCT02026362	Multiple Antigen Specific Cell Therapy (MASCT) for Hepatocellular Carcinoma(HCC) Patients…(HCC DC CTL)	Phase 1 / Phase 2	suspended	Jan 3, 2014	HRYZ Biotech Co.	Interim analysis	Efficacy / futility
NCT01784978	Efficacy Study of Sunitinib and Everolimus (Rotational vs Sequential Arm) in Pats. With m…(SUNRISES)	Phase 2	terminated	Feb 6, 2013	Associació per a la Recerca Oncologica, Spain	Lack of recruitment	Enrollment / accrual
NCT02831179	Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and…	Phase 1	withdrawn	Jul 13, 2016	Vanderbilt-Ingram Cancer Center	Loss of funding support	Funding
NCT01145508	Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With…	Phase 2	terminated	Jun 16, 2010	National Cancer Institute (NCI)	Poor accrual	Enrollment / accrual
NCT02121925	Registry Measuring the Impact of Adding RNA Expression Testing on Referral Decisions in…(ONC003)	—	terminated	Apr 24, 2014	Myriad Genetic Laboratories, Inc.	Company decision to terminate	Sponsor / business decision
NCT02585687	Liver Perfusion MRI With Quantification of Tumoral Perfusion for Early Assessment of the…(ETAFIRM)	N/A	terminated	Oct 23, 2015	Hospices Civils de Lyon	problems with enrollment	Enrollment / accrual
NCT01489410	Comparing Lipiodol/Ethanol With Drug-eluting Beads (DEB) for Hepatocellular Carcinoma	N/A	withdrawn	Dec 9, 2011	University of Minnesota	Insufficient staff	Other (stated, no rule matched)
NCT01866423	Orteronel in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer	Phase 2	terminated	May 31, 2013	University of Southern California	Not progressing toward scientific goals	Other (stated, no rule matched)
NCT01319539	MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer	Phase 2	terminated	Mar 21, 2011	National Cancer Institute (NCI)	terminated early, due to toxicity	Safety / toxicity
NCT01668017	A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein…	Phase 1	terminated	Aug 17, 2012	Merck KGaA, Darmstadt, Germany	The sponsor decided not to conduct the expansion part of trial (part 2)	Sponsor / business decision
NCT02821533	Chemoembolization for Hepatocellular Carcinoma	Phase 2	terminated	Jul 1, 2016	Chinese University of Hong Kong	Poor case accrual	Enrollment / accrual
NCT02715102	Circulating Tumor DNA in Patients at High Risk for Lung Cancer	—	terminated	Mar 22, 2016	Pathway Genomics	Patient accrual was slow due to exclusion of patients with prior cancers	Enrollment / accrual
NCT02089802	Optimizing Pazopanib Exposure in RCC Patients(OPERA)	Phase 2	terminated	Mar 18, 2014	Interessenverband zur Qualitätssicherung der Arbeit niedergelassener Uro-Onkologen in Deutschland e.	Early termination due to lack of recruitment	Enrollment / accrual
NCT01191385	GIDEON Non-Nexavar Arm - HCC Patients Who Are Treated With Any Therapy Other Than Nexavar…	—	withdrawn	Aug 30, 2010	Bayer	Study is officially cancelled bevore FPFV.	Other (stated, no rule matched)
NCT00004221	Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients…	Phase 2	terminated	Aug 25, 2003	Gynecologic Oncology Group	not stated	Not stated
NCT02959359	DAA in the Risk of Recurrence After Curative Treatment of HCC	Phase 4	withdrawn	Nov 9, 2016	Taipei Veterans General Hospital, Taiwan	The supplies of study drug were halted by Gilead Sciences Ltd.	Other (stated, no rule matched)
NCT02223975	Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease(Vulval VS)	—	suspended	Aug 22, 2014	Gloucestershire Hospitals NHS Foundation Trust	Study suspended pending further funding	Funding
NCT01114256	FNA Tumor Sampling for CD137 Modulation: A Pilot Study	—	terminated	May 3, 2010	Stanford University	not stated	Not stated
NCT01598038	Relation Between Safety Endpoints and Everolimus Trough Blood Level in Advanced Renal…	N/A	terminated	May 15, 2012	Centre Francois Baclesse	not stated	Not stated
NCT02928263	Healthcare Cost and Resource Utilization Related to Metastatic Renal Cell Carcinoma…	—	withdrawn	Oct 10, 2016	Bristol-Myers Squibb	Business objectives have changed	Sponsor / business decision
NCT01754519	Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer…	Phase 2	terminated	Dec 21, 2012	Roswell Park Cancer Institute	IDE not submitted	Other (stated, no rule matched)
NCT00085410	Bortezomib in Treating Patients With Unresectable Locally Advanced or Metastatic…	Phase 2	terminated	Jun 11, 2004	National Cancer Institute (NCI)	The trial was discontinued early due to no confirmed partial responses.	Other (stated, no rule matched)

Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.

Data updated 23 days agoSource updated Feb 20, 2018source: clinicaltrials

Terminated, withdrawn and suspended studies

Stated reasons by category

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