Clinical trial · Observational
Long-Term Patient Reported Outcomes Following Surgery for Spinal Intradural Tumours
Long-term Patient Reported Outcomes Following Surgery for Spinal Intradural Tumours: A Cross-sectional Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Oct 1, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20261001-000001
Summary
Brief summary (as posted)
The objective of this study is to identify the long-term impact of PSIDT tumours and their treatment on patient HRQoL for those managed at the Walton Centre NHS Foundation Trust (WCFT), which provides tertiary care to a catchment population of 3.5 million so will manage many patients with these rare tumours. Additionally, the availability of Spine-Tango allows the identification of patients spanning a long duration of follow up. By encompassing a broad anatomical subset, we hope that this will be more sensitive to factors influencing PROs. Additionally, we aim to capture trends that may be more meaningful to patients by performing this long-term follow up. No studies have so far attempted to assess longer term patient reported HRQoL outcomes in this patient group. This study will better identify patient priorities, guide future research directions and holistic care planning. This will be achieved through a cross-sectional cohort study, which will evaluate PROs using five validated questionnaires at a single time point following surgery. These PRO measures will assess HRQoL. The definition of PRO includes the use of subjective measures such as those used for assessment of HRQoL
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Spinal Tumors | Spinal Cord Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Long-term patient-reported health-related quality of life (HRQoL)
- timeFrame
- 3-10 years following completion of spinal intradural tumour surgery
- description
- All patients will receive a study-specific questionnaire booklet identifying: * Active medical problems * Current medications (and indications) as well as smoking status * calculation of a Frankel Grade and level of deficit * Current employment status * Health-related quality of life questionnaires This will allow for collection and analysis of long-term health related quality of life data
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who received surgery at the WCFT for a PSIDT, both intramedullary and extramedullary covering the time period 2011 to 2018 * Patients aged ≥16 years at the time of surgery for a PSIDT * Able to communicate effectively using the English language * Capacity to complete the study consent form Exclusion Criteria: * Patients aged \<16 years at the time of surgery for a PSIDT * Patients with metastatic spinal intradural tumours * Patients with a previous spinal operation for a non-intradural tumour related indication * Patients with a primary operation for a PSIDT before 2011 * Patients with any other congenital or acquired neurological disorder prior to diagnosis of SIDT * Patients considered to lack capacity to consent to participate in this study (e.g. due to a significant neurological deficit or cognitive disorder) * Patients with \>1 tumour as part of a syndrome (e.g. neurofibromatosis or Von Hippel Lindau)
References
Publications (0)
Data not yet available