Clinical trial · Observational
The LifeMeds Cohort
The LifeMeds Cohort: Joining Forces to Assess (Determinants of) Lifestyle Behavior, Morbidity and Mortality Among Multimorbid Individuals
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260930-000001
Summary
Brief summary (as posted)
The goal of this observational study is to investigate lifestyle behaviours, their determinants, and their associations with health outcomes in adults with multimorbidity, defined as the presence of at least two lifestyle-related chronic diseases, including cardiovascular disease, type 2 diabetes, chronic respiratory disease, and/or cancer. The main questions it aims to answer are: * What lifestyle trajectories can be identified over time in individuals with multimorbidity, how do these trajectories differ across multimorbidity profiles, and which psychological, social, and sociodemographic factors are associated with these trajectories? * How are lifestyle trajectories associated with morbidity, mortality, health-related quality of life, and other major health outcomes over time? Participants will complete one annual questionnaire during a follow-up period of ten years.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Cardio Vascular Disease | — | UNRESOLVED | — |
| Chronic Respiratory Conditions | — | UNRESOLVED | — |
| Multimorbidity | — | UNRESOLVED | — |
| Type 2 Diabetes | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Multimorbid individuals
- description
- Individuals who have been diagnosed with at least two of the following chronic diseases: type 2 diabetes mellitus, cardiovascular disease, chronic respiratory diseases and/or cancer.
Primary outcomes (11)
- measure
- Changes in physical activity levels using the Short QUestionnaire to ASsess Health-enhancing physical activity (SQUASH).
- timeFrame
- From enrollment to the end of the study at 10 years
- description
- The SQUASH is a validated questionnaire that assesses habitual physical activity across commuting, household, leisure-time, and occupational domains. Repeated assessments over time will enable the evaluation of changes in physical activity levels.
- measure
- Changes in dietary intake using a self-composed questionnaire based on the Dutch Healthy Diet Index (DHDI).
- timeFrame
- From enrollment to the end of the study at 10 years
- description
- Dietary intake is assessed using a self-composed questionnaire based on the Dutch Healthy Diet Index (DHDI). The questionnaire captures key aspects of diet quality and adherence to dietary recommendations. Repeated assessments over time will enable the evaluation of changes in dietary behaviours.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosed with two or more of the following diseases: type 2 diabetes, cancer, cardiovascular disease and/or chronic respiratory diseases. * Aged 18 years or older Exclusion Criteria: * Diagnosed with significant cognitive impairment (e.g. major neurocognitive disorder)
References
Publications (0)
Data not yet available