Clinical trial · Interventional
Modified Saddle Block vs Spinal Anesthesia for TURP
Comparison of Modified Saddle Block With Spinal Anesthesia Among Patients Undergoing Transurethral Resection of Prostate Cancer; A Randomized Control Trial at a Tertiary Care Hospital
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded. Participants will be randomly assigned to receive either spinal anesthesia or a modified saddle block using hyperbaric bupivacaine administered in the lower back. The position of the patient after injection will differ according to the assigned anesthetic technique. The level of numbness produced by the anesthesia will be assessed, and patients with inadequate anesthesia will be excluded. Blood pressure and heart rate will be monitored regularly during surgery. Any significant decrease in blood pressure will be treated with intravenous phenylephrine. Any need to change to general anesthesia during the procedure will also be recorded.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hypotension During Surgery | — | UNRESOLVED | — |
| Saddle Block Anesthesia | — | UNRESOLVED | — |
| Spinal Anesthesia | — | UNRESOLVED | — |
| TURP(Transurethral Resection of Prostate) | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Saddle block | Drug | — | UNRESOLVED |
| Spinal Anesthesia (bupivacaine) | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group Saddle
- description
- Patients in this group will receive Saddle block
- interventionNames
- Drug: Saddle block
- type
- ACTIVE_COMPARATOR
- label
- Group Spinal anesthesia
- description
- Patients in this group will receive Spinal anesthesia
- interventionNames
- Drug: Spinal Anesthesia (bupivacaine)
Primary outcomes (1)
- measure
- Maximum fall in Mean Arterial Pressure
- timeFrame
- Peri-operative from From induction of anesthesia until completion of surgery
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 40 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Age 40- 90 years * Elective TURP surgery under Neuraxial Anesthesia * ASA class I and II Exclusion Criteria: * Contraindication to Neuraxial anesthesia * Allergic to study medications * Lack of consent
References
Publications (1)
- BACKGROUNDShahid N, Iqbal MW, Haque SN, Rashid AM, Shaukat S. Effectiveness Of Saddle Block Vs Spinal Anaesthesia In Turp: An Open Label Randomized Control Trial. J Ayub Med Coll Abbottabad. 2023 Feb-Mar;35(1):127-132. doi: 10.55519/JAMC-01-11451. PMID 36849392