Clinical trial · Observational
Skin Cancer Among Outdoor Workers
Skin Cancer Among Outdoor Workers: A Nationwide Analysis of Occupational Claims and Disability Burden
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
This observational study examines skin cancer among workers who may have prolonged occupational exposure to sunlight. Long-term exposure to ultraviolet radiation from the sun is an important risk factor for several types of skin cancer, particularly among people who work outdoors for many years. The study will use routinely collected administrative and medical data to describe the characteristics of workers with recognized skin cancer, including age, sex, geographic region, type of skin cancer, occupational characteristics, and disability-related outcomes. Trends over time and differences between population groups will also be evaluated when the available data permit. The purpose of the study is to better understand the burden of skin cancer associated with occupational sun exposure and to identify groups of workers who may be at increased risk. The findings may help support improved prevention, earlier detection, workplace sun-protection measures, and occupational health policies for outdoor workers.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Basal Cell Carcinoma of Skin | Skin Basal Cell Carcinoma | ALIAS | 0.90 |
| Melanoma (Skin Cancer) | Melanoma | ONTOLOGY_EXACT | 0.85 |
| Squamous Cell Cancer of Head and Neck (SCCHN) | Head and Neck Squamous Cell Carcinoma | ALIAS | 0.85 |
| Sun Exposure | — | UNRESOLVED | — |
| Work Injury | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Skin cancer in workers under sun
- description
- Workers with documented or recognized skin cancer potentially associated with occupational exposure to solar ultraviolet radiation. The cohort includes individuals with available administrative, occupational, medical, and disability-related records during the study period. Skin cancers will be classified, when data permit, as basal-cell carcinoma, squamous-cell carcinoma, melanoma, or other malignant skin tumors. Demographic characteristics, occupational features, geographic distribution, temporal trends, and disability outcomes will be evaluated. This is an observational study; no intervention or treatment is assigned as part of the study.
Primary outcomes (1)
- measure
- Number and Proportion of Recognized Occupational Skin Cancer Cases by Cancer Type
- timeFrame
- Baseline (at initial recognition of the occupational skin cancer claim)
- description
- Cancer type was determined at the initial recognition of each occupational skin cancer claim. The number and proportion of recognized cases were summarized by cancer type, including basal-cell carcinoma, squamous-cell carcinoma, melanoma, and other malignant skin tumors, for claims recorded in the national administrative database from January 1, 2018 through December 31, 2025.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Individuals with a documented or recognized occupational skin cancer during the predefined study period. * Skin cancer potentially associated with occupational exposure to solar ultraviolet radiation. * Diagnoses including basal-cell carcinoma, squamous-cell carcinoma, melanoma, or other malignant skin tumors when diagnostic classification is available. * Availability of sufficient administrative, occupational, medical, or disability-related information for inclusion in the analysis Exclusion Criteria: \-
References
Publications (5)
- BACKGROUNDSchmitt J, Seidler A, Diepgen TL, Bauer A. Occupational ultraviolet light exposure increases the risk for the development of cutaneous squamous cell carcinoma: a systematic review and meta-analysis. Br J Dermatol. 2011 Feb;164(2):291-307. doi: 10.1111/j.1365-2133.2010.10118.x. PMID 21054335
- BACKGROUNDPega F, Momen NC, Streicher KN, Leon-Roux M, Neupane S, Schubauer-Berigan MK, Schuz J; Technical Advisory Group on Occupational Burden of Disease Estimation; Baker M, Driscoll T, Guseva Canu I, Kiiver HM, Li J, Nwanaji-Enwerem JC, Turner MC, Viegas S, Villeneuve PJ. Global, regional and national burdens of non-melanoma skin cancer attributable to occupational exposure to solar ultraviolet radiation for 183 countries, 2000-2019: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury. Environ Int. 2023 Nov;181:108226. doi: 10.1016/j.envint.2023.108226. Epub 2023 Nov 8. PMID 37945424
- BACKGROUNDWendt A, Mohner M. Occupational solar exposure and basal cell carcinoma. A review of the epidemiologic literature with meta-analysis focusing on particular methodological aspects. Eur J Epidemiol. 2024 Jan;39(1):13-25. doi: 10.1007/s10654-023-01061-w. Epub 2024 Jan 3. PMID 38170370
- BACKGROUNDSlavinsky V, Helmy J, Vroman J, Valdebran M. Solar ultraviolet radiation exposure in workers with outdoor occupations: a systematic review and call to action. Int J Dermatol. 2024 Mar;63(3):288-297. doi: 10.1111/ijd.16877. Epub 2023 Oct 18. PMID 37853576
- BACKGROUNDKristensen I, Iversen IB, Fenger-Gron M, Kolstad HA, Wurtz ET, Turner MC, Grandahl K, Schmidt SAJ, Stokholm ZA. Occupational solar ultraviolet radiation and incidence of non-melanoma skin cancer in a nationwide cohort. Environ Pollut. 2025 Dec 1;386:127275. doi: 10.1016/j.envpol.2025.127275. Epub 2025 Oct 15. PMID 41106796