Clinical trial · Interventional
Anthocyanin-Rich Berry Supplementation in Patients With Colorectal Cancer
Effect of Anthocyanins on the Immune Response During Colorectal Cancer Treatment in Patients Over 65 Years of Age Using Freeze-Dried Black Raspberry and Strawberry Extracts
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 16, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260916-000001
Summary
Brief summary (as posted)
This prospective, open-label interventional study evaluated the effects of short-term supplementation with an anthocyanin-rich freeze-dried black raspberry and strawberry preparation in patients undergoing treatment for colorectal cancer. The study assessed the tolerability of the intervention and longitudinal changes in nutritional status and selected inflammatory and biochemical biomarkers. Participants received the anthocyanin-rich supplement for 21 consecutive days in addition to standard oncological treatment and were assessed at baseline and during follow-up.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Anthocyanin-Rich Freeze-Dried Berry Supplement | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Anthocyanin-Rich Berry Supplementation
- interventionNames
- Dietary Supplement: Anthocyanin-Rich Freeze-Dried Berry Supplement
- type
- NO_INTERVENTION
- label
- Baseline comparator group
Primary outcomes (1)
- measure
- Change in Inflammatory Biomarkers
- timeFrame
- Baseline, Week 4, and Week 12
- description
- Change in circulating inflammatory biomarkers, including C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1 alpha (IL-1α), and tumor necrosis factor alpha (TNF-α), compared with baseline.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * (1) histologically confirmed primary colorectal adenocarcinoma; (2) qualification for surgical treatment, neoadjuvant chemoradiotherapy, or systemic chemotherapy; (3) ability to receive oral supplementation; and (4) Eastern Cooperative Oncology Group (ECOG) performance status ≤2. (5)Age ≥65 years Exclusion Criteria: * (1) gastrointestinal obstruction; (2) advanced cardiac or respiratory failure; (3) severe renal or hepatic insufficiency; and (4) food allergies or hypersensitivity that could interfere with administration of the study supplement.
References
Publications (1)
- BACKGROUNDJaglarz-Bialy K, Konturek A, Jagla J, Orzel A, Krol-Dyrek K, Fraczek J, Krosniak M. The analysis of the composition and antioxidant properties of freeze-dried chokeberry, strawberry, blackberry and selected raspberry fruits. Folia Med Cracov. 2024 Dec 30;64(4):47-57. doi: 10.24425/fmc.2024.153272. PMID 40899077