Clinical trial · Observational
Acute Ischemic Stroke in Patients With Active Cancer
Clinical Characteristics and Stroke Recurrence in Patients With Acute Ischemic Stroke and Active Cancer: The CAT-AIS Multicenter Prospective Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
The goal of this multicenter prospective observational study, conducted at 24 hospitals in Japan, is to learn about recurrent ischemic stroke in people with active cancer who develop acute ischemic stroke. One of the main objectives is to evaluate how often ischemic stroke recurs during follow-up. The main questions this study aims to answer are: * How often does ischemic stroke recur within 3 months after the initial stroke? * Which clinical factors may be associated with recurrent ischemic stroke? * What other clinical outcomes occur during follow-up? Participants will receive medical care determined by their treating physicians. Researchers will collect information about participants' cancer, stroke characteristics, test results, treatments, recurrent ischemic stroke, and other clinical outcomes. Researchers will also explore whether clinical factors are associated with recurrent ischemic stroke and other outcomes. This study will not assign participants to a specific treatment.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Active Cancer | — | UNRESOLVED | — |
| Acute Ischemic Stroke | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Participants with acute ischemic stroke and active cancer
- description
- Participants with active cancer who develop acute ischemic stroke and are enrolled prospectively at participating hospitals. Clinical information, treatments, recurrent ischemic stroke, and other outcomes will be collected during follow-up.
Primary outcomes (1)
- measure
- Percentage of Participants With Recurrent Ischemic Stroke Within 3 Months
- timeFrame
- From enrollment through 3 months of follow-up
- description
- The percentage of participants who experience recurrent ischemic stroke during follow-up. Recurrent ischemic stroke will be determined according to the criteria prespecified in the study protocol.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Acute ischemic stroke diagnosed within 7 days after symptom onset or the time last known well. 2. Active cancer at the time of the index stroke, as defined below. Exclusion Criteria: 1. The patient or a legally acceptable representative indicates that the patient does not wish to participate. 2. The investigator considers enrolment inappropriate.
References
Publications (0)
Data not yet available