Clinical trial · Observational
Preoperative Sarcopenia and Postoperative Outcomes in Older Patients With Gastrointestinal Cancer
The Effect of Preoperative Sarcopenia on Postoperative Prognosis in Older Patients With Gastrointestinal Cancer: A Prospective Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260915-000001
Summary
Brief summary (as posted)
This prospective cohort study aims to evaluate the association between preoperative sarcopenia and postoperative outcomes in patients aged 60 years or older undergoing elective surgery for gastrointestinal cancer. Sarcopenia will be assessed preoperatively using the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria, including muscle strength, muscle mass, and physical performance, together with the Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls (SARC-F) questionnaire and calf circumference measurement. Participants will be followed for 90 days after surgery. Postoperative complications, length of hospital stay, and 30-day and 90-day mortality will be evaluated.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastrointestinal Neoplasms | Digestive System Neoplasm | ALIAS | 0.90 |
| Sarcopenia | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Preoperative Sarcopenia Status | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Participants With Preoperative Sarcopenia
- description
- Participants aged 60 years or older undergoing elective surgery for gastrointestinal cancer who are identified as having preoperative sarcopenia according to the EWGSOP2 criteria. Participants will receive standard surgical and perioperative care without any study-assigned intervention.
- interventionNames
- Other: Preoperative Sarcopenia Status
- label
- Participants Without Preoperative Sarcopenia
- description
- Participants aged 60 years or older undergoing elective surgery for gastrointestinal cancer who are not identified as having preoperative sarcopenia according to the EWGSOP2 criteria. Participants will receive standard surgical and perioperative care without any study-assigned intervention.
- interventionNames
- Other: Preoperative Sarcopenia Status
Primary outcomes (1)
- measure
- Incidence of postoperative complications
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * Age 60 years or older * Diagnosis of gastrointestinal system cancer * Scheduled to undergo elective surgical treatment * Considered operable based on routine clinical evaluation * Ability to complete the preoperative sarcopenia assessments * Provision of written informed consent Exclusion Criteria: * Age younger than 60 years * Undergoing emergency surgery * Inability to complete the required preoperative sarcopenia assessment
References
Publications (0)
Data not yet available