Clinical trial · Interventional
A Manualised Post-Traumatic Growth Intervention For People With Hematological Cancers In Greece
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 11, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260911-000001
Summary
Brief summary (as posted)
This clinical trial aims to determine whether a manualised group intervention for people with blood cancers can help them experience positive psychological changes following their diagnosis, known as post-traumatic growth. Participants receiving the intervention will be compared with those receiving usual care and placed on a waiting list. Participants will be randomly allocated to either the group intervention or the usual care/waiting-list group. The study will also explore how this intervention could be implemented within the Greek healthcare system. The study aims to answer the following main questions: (1) Does this psychological group intervention increase post-traumatic growth in people with blood cancers? (2) Does this intervention improve other outcomes, including anxiety, depression, quality of life, psychological well-being, cognitive functioning, distress, illness understanding and routine blood markers? Participants will: (1) Attend nine weekly face-to-face group sessions in Greek, each lasting approximately two hours, with other people living with blood cancers. (2) Receive a detailed manual/workbook covering the session content and be encouraged to use it between sessions. (3) Have the opportunity to participate in an optional outdoor activity of their choice. (4) Complete questionnaires and a brief cognitive assessment before and after the intervention, together with other assessments as required. Participation is voluntary and free of charge. Some participants may experience mild emotional discomfort when discussing their experiences; however, psychological support will be available if needed. The findings will help researchers determine whether this group intervention can support people living with blood cancers and inform the future implementation of similar interventions within the Greek healthcare system.
Conditions
Conditions (16)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Lymphoid Leukemia (ALL) | Acute Lymphoblastic Leukemia | ALIAS | 0.85 |
| Blood Cancers | — | UNRESOLVED | — |
| Bone Marrow Transplant | — | UNRESOLVED | — |
| Chronic Myeloid Leukemia (CML) | Chronic Myeloid Leukemia, BCR-ABL1 Positive | ALIAS | 0.85 |
| Hematological Cancers | — | UNRESOLVED | — |
| Hematological Malignancies | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
| Hematological Neoplasm | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
| Leukemia | Leukemia |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| A manualised post-traumatic growth intervention for people with hematological cancers | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control group
- description
- Control group, waiting list, usual care
- type
- EXPERIMENTAL
- label
- Intervention
- description
- Interventional arm during which participants join a weekly peer group
- interventionNames
- Behavioral: A manualised post-traumatic growth intervention for people with hematological cancers
Primary outcomes (1)
- measure
- Posttraumatic Growth Inventory - X (PTGI-X)
- timeFrame
- Pre-intervention (baseline), post-intervention (9 weeks post-baseline), and approximately at 3, 6, and 12 months following the post-intervention assessment.
- description
- PTGI-X is a validated, 25-item, theory-driven questionnaire scored on a 6-point Likert scale, with scores ranging from 0-125, where higher scores indicate higher PTG.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Having a diagnosis of a hematological cancer * Having completed the planned hospital admission and related treatments * Having no more than 5 years since the initial diagnosis Exclusion Criteria: * Being in active psychological or psychiatric treatment * Having an unmanaged mental health difficulty * Having a severe cognitive impairment * Being unable to give informed consent * Being unable to read or speak Greek * Having one or more cancer relapses * Diagnosed with another type of cancer within 5 years prior to recruitment * Having a life expectancy of less than one year
References
Publications (2)
- BACKGROUNDTedeschi, R. G., Shakespeare-Finch, J., & Taku, K. (2018). Posttraumatic growth: Theory, research, and applications. Routledge.
- RESULTVrontaras N, Koulierakis G, Ntourou I, Karakatsoulis G, Sergentanis TNu, Kyrou D, Kapetanakis A, Karademas E, Karamanidou C. Psychosocial interventions on the posttraumatic growth of adults with cancer: A systematic review and meta-analysis of clinical trials. Psychooncology. 2023 Dec;32(12):1798-1826. doi: 10.1002/pon.6241. Epub 2023 Nov 14. PMID 37964424