Ultrasound-Guided Emulsification Therapy in the Clinical Treatment of Subcutaneous Lipomas

Background:Lipomas are the most common benign soft tissue tumors, traditionally treated by open surgical excision. However, open surgery is associated with relatively large incisions, prolonged recovery, and visible scarring. While liposuction offers a less invasive alternative, it often achieves unsatisfactory clearance rates for lipomas with significant fibrotic components, leading to higher recurrence rates. Study Objective:This study aims to investigate the safety and efficacy of CUSA in the minimally invasive treatment of lipomas. Study Methods:this is a single-center, prospective clinical study. A total of 30 eligible patients with clinically diagnosed lipomas scheduled for surgical treatment will be enrolled. All participants will undergo minimally invasive tumor resection using the CUSA system. The primary outcome measure is tumor clearance rate .Secondary outcome measures include operation time, intraoperative blood loss, postoperative pain score, complication rate, recurrence rate, cosmetic outcome, and patient satisfaction. Patients will be followed up for 6 months after treatment. Study Significance:The results of this study will provide evidence-based clinical support for the application of CUSA in the minimally invasive treatment of lipomas, particularly for lesions with abundant fibrotic components, and may help optimize treatment strategies and improve patient outcomes.

Sex

All

Minimum age

18 Years

Maximum age

60 Years

Inclusion Criteria:

1\. Aged 18 to 60 years; 2. Subcutaneous lipoma confirmed by ultrasound and needle biopsy pathology; 3. Maximum diameter of the lipoma greater than 1 cm; 4. Lipoma located on the trunk, extremities, or neck (excluding the head and face); 5. Lipoma located in the subcutaneous fat layer with a safe distance from the skin and deep tissues; 6. Patients with explicit demand for minimally invasive and cosmetic treatment; 7. Voluntarily participate in the study and sign the informed consent form; 8. Willing to cooperate with preoperative examinations, intraoperative procedures, and postoperative follow-up.

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Exclusion Criteria:

1. Coagulation dysfunction or currently receiving anticoagulant therapy;
2. Lipoma located in the head and face or within the muscle layer;
3. Atypical lipoma or liposarcoma indicated by needle biopsy pathology;
4. Ulceration, redness, swelling, or infection of the skin overlying the lipoma;
5. Pregnant or lactating women;
6. Severe dysfunction of vital organs such as the heart, liver, or kidney;
7. Severe mental illness or cognitive impairment;
8. Previous history of surgery or radiotherapy at the same site;
9. Currently participating in other clinical studies. -

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