Clinical trial · Interventional
Different Acupoint Stimulation for Postoperative Gastrointestinal Dysfunction in Primary Liver Cancer Patients
Application of Different Acupoint Stimulation Methods in the Prevention and Management of Postoperative Gastrointestinal Dysfunction in Patients With Primary Liver Cancer: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Brief Summary (Plain Language) The purpose of this clinical trial is to evaluate and compare the effects of four different intervention measures on preventing and managing postoperative gastrointestinal dysfunction in patients with primary liver cancer. The four measures include herbal acupoint application, transcutaneous acupoint electrical stimulation, the combination of the above two acupoint stimulation methods, and routine clinical nursing. This study aims to provide scientific evidence for the clinical application of acupoint stimulation therapies in postoperative rehabilitation of liver cancer patients. The main research question of this study is whether acupoint stimulation interventions can effectively improve postoperative gastrointestinal recovery in primary liver cancer patients. The primary outcome measure is the time to first postoperative anal exhaust, which is a core indicator to reflect the recovery of gastrointestinal function after surgery. By comparing the differences in gastrointestinal recovery among the four groups, this trial will clarify the optimal acupoint intervention scheme to prevent and relieve postoperative gastrointestinal dysfunction in primary liver cancer patients, so as to improve patients' postoperative rehabilitation quality.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Primary Liver Cancer | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Acupoint application | Other | — | UNRESOLVED |
| Combined Intervention | Other | — | UNRESOLVED |
| routine care | Other | — | UNRESOLVED |
| TAES | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Acupoint Application
- interventionNames
- Other: Acupoint application
- type
- EXPERIMENTAL
- label
- TAES
- interventionNames
- Device: TAES
- type
- EXPERIMENTAL
- label
- Combined Intervention
- interventionNames
- Other: Combined Intervention
- type
- ACTIVE_COMPARATOR
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed with primary liver cancer scheduled for initial partial hepatectomy or laparoscopic partial hepatectomy. * Aged between 18 and 75 years old. * Clear consciousness and ability to communicate in writing. * Voluntary participation with signed informed consent. Exclusion Criteria: * Patients receiving concurrent chemotherapy. * Patients with adhesive plaster allergy or allergic constitution. * Patients with local skin damage, infection or dermatitis at acupoint sites. * Patients with cognitive dysfunction. * Patients complicated with preoperative gastrointestinal dysfunction or with a history of gastrointestinal surgery. * Patients undergoing associating liver partition and portal vein ligation for staged hepatectomy (ALPPS). * Patients transferred to the intensive care unit (ICU) after surgery. * Patients with implanted cardiac pacemakers.
References
Publications (7)
- BACKGROUNDWang MX. Effect of acupoint application during Chen period on gastrointestinal function recovery in patients with primary liver cancer after laparoscopic surgery[D]. Guangzhou University of Chinese Medicine, 2023.
- BACKGROUNDShi XL, Li H, Bian LF, et al. Summary of best evidence for prevention and management of postoperative gastrointestinal dysfunction in patients with liver cancer. Journal of Enhanced Recovery After Surgery, 2024, 7 (4): 145-151.
- BACKGROUNDLi S, Liu KX, Deng XM, et al. Expert consensus on prevention and treatment of postoperative gastrointestinal dysfunction. International Journal of Anesthesiology and Resuscitation, 2021, 42 (11): 1133-1142.
- BACKGROUNDExpert Committee for the Guidelines for Diagnosis and Treatment of Primary Liver Cancer, Zhou J. Guidelines for Diagnosis and Treatment of Primary Liver Cancer (2024 edition). Chinese Journal of Clinical Medicine, 2024, 31(2): 277-334.
- BACKGROUNDCheng XN, Zhang X, Ji J, Zhou J. [Acupoints selection rules of acupuncture and moxibustion for promoting gastrointestinal function recovery after intestinal cancer surgery based on complex network analysis]. Zhen Ci Yan Jiu. 2024 Oct 25;49(10):1107-1120. doi: 10.13702/j.1000-0607.20230829. Chinese. PMID 39433373
- BACKGROUNDJiang T, Li J, Meng L, Wang J, Zhang H, Liu M. Effects of transcutaneous electrical acupoint stimulation on gastrointestinal dysfunction after gastrointestinal surgery: A meta-analysis. Complement Ther Med. 2023 May;73:102938. doi: 10.1016/j.ctim.2023.102938. Epub 2023 Feb 25. PMID 36842636
- BACKGROUNDArfa S, Turco C, Lakkis Z, Bourgeois S, Fouet I, Evrard P, Sennegon E, Roucoux A, Paquette B, Devaux B, Rietsch-Koenig A, Heyd B, Doussot A. Delayed return of gastrointestinal function after hepatectomy in an ERAS program: incidence and risk factors. HPB (Oxford). 2022 Sep;24(9):1560-1568. doi: 10.1016/j.hpb.2022.03.014. Epub 2022 Apr 5. PMID 35484074