Clinical trial · Observational
CT Imaging and Clinical Features to Predict Outcomes in Patients With Gastric Cancer
Prospective Validation of a CT Radiomics-Based Model Combined With Clinical Features for Prognosis Prediction in Gastric Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this prospective observational study is to evaluate how well a previously developed prediction model can estimate outcomes in adults with gastric cancer. The model combines information from computed tomography (CT) images obtained before treatment with routine clinical information. The main questions are how well the model predicts how long participants live after treatment begins and whether their cancer progresses. Participants will receive their usual medical care. Researchers will collect pretreatment CT images, basic clinical and tumor information, laboratory and tumor marker results, treatment information, and follow-up outcomes obtained during routine care. These data will be entered into the predefined prediction model, and the model's predictions will be compared with what actually happens during follow-up. The study will not change the participants' usual treatment. Model predictions will be used for research purposes only and will not be used to make treatment decisions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention (observational study) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Prospective Gastric Cancer Validation Cohort
- description
- Adults with newly diagnosed gastric cancer will be prospectively enrolled at the study center. Eligible participants will have pretreatment CT imaging and relevant clinical data available for analysis. Participants will receive routine clinical care according to their clinical condition. Pretreatment CT imaging and clinical data will be analyzed using the predefined prognostic model, and model predictions will be compared with observed clinical outcomes during follow-up.
- interventionNames
- Other: No intervention (observational study)
Primary outcomes (1)
- measure
- Overall Survival (OS)
- timeFrame
- From initiation of treatment until death or last follow-up, assessed up to 12 months
- description
- Overall survival is defined as the time from initiation of initial treatment to death from any cause. Participants who are alive at the last available clinical follow-up will be censored at the date of last follow-up. Survival status will be obtained from medical records, telephone follow-up, and death certificates.
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically or pathologically confirmed gastric cancer and receiving treatment at the study center. * Age ≥18 years. * Complete pretreatment CT imaging data available from the study center. Exclusion Criteria: * Pretreatment CT images of insufficient quality for analysis. * Incomplete clinical data. * Presence of another malignant tumor in addition to gastric cancer.
References
Publications (0)
Data not yet available