Clinical trial · Observational
Establishment of a Multi-omics Prediction Model for Early Triple-negative Breast Cancer Based on UPGRADE-TNBC Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Based on the UPGRADE-TNBC study, a high-quality TNBC sample repository was established. By integrating multi-source data-including clinical information, radiomics, pathological images, and molecular sequencing-and innovatively incorporating a meta-learning strategy, a treatment response prediction model based on multimodal small-sample learning was developed. This approach aims to optimize drug combinations and precisely identify patient subgroups likely to benefit from treatment, thereby providing a new paradigm for personalized therapy in early-stage TNBC.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Meta-Learning | — | UNRESOLVED | — |
| Multimodal | — | UNRESOLVED | — |
| Predictive Models | — | UNRESOLVED | — |
| Triple -Negative Breast Cancertriple | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Collect data | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- The Population in the UPGRADE-TNBC Study（early-stage triple-negative breast cancer）
- interventionNames
- Other: Collect data
Primary outcomes (1)
- measure
- Model building
- timeFrame
- 2 years
- description
- A predictive model for neoadjuvant therapy in TNBC was successfully established
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * The UPGRADE-TNBC Study Population Exclusion Criteria: * Populations outside the UPGRADE-TNBC study
References
Publications (0)
Data not yet available