Clinical trial · Interventional
Training on Systemic and Organ Spec. PM in PC
Impact of Prescribed Physical Training on Systemic and Organ Specific Prognostic Markers in Prostate Cancer
NCT07768917CI-TRIAL-00122279not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research is being done to assess the impact of a supervised and structured strength and conditioning program on cardiac remodeling in participants with prostate cancer undergoing treatment with external beam radiation therapy and at least 6 months of Gonadotropin-releasing hormone (GnRH) therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Exercise Program
- description
- Participants will undergo a 6-month exercise program.
- interventionNames
- Other: Exercise
Primary outcomes (17)
- measure
- Left Ventricular Ejection Fraction
- timeFrame
- At the start of the exercise program for up to 6 month after exercise program.
- description
- Left ventricular ejection fraction (%) as measured by echocardiogram
- measure
- Left Ventricular Mass
- timeFrame
- Time Frame: At the start of the exercise program for up to 6 month after exercise program.
- description
- Left ventricular mass (g) as measured by echocardiogram
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Have histologically or cytologically confirmed adenocarcinoma of the prostate * Have not received GnRH agonist or antagonist within the last 12 months * Planned for initiation of a GnRH agonist or antagonist or bilateral orchiectomy with an intended treatment duration of ≥ 6 months * Planned for initiation of radiation therapy to the prostate. * ECOG performance status of 0 or 1 * Ability to understand and the willingness to sign a written informed consent document * Baseline serum total testosterone level \> 230 ng/dL (the accepted threshold for testosterone supplementation) * Speak English -\>18 years of age Exclusion Criteria: * Has a known medical condition that makes the subject unable to participate in exercise testing (e.g. unrevascularized coronary artery disease, moderate/severe osteoarthritis, prior stroke, or other conditions) * Receiving or planned to receive other cancer therapy not included in Eligibility Criterion 3.1.3 (other than an antiandrogen during the first month of therapy) * The following populations will not be considered for inclusion on this trial.
References
Publications (0)
Data not yet available
No reference posted for this study.