Clinical trial · Observational
Impact of Obesity on Textbook Outcome Achievement in Minimally Invasive Colorectal Cancer Surgery
NCT07756450CI-TRIAL-00123826completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Textbook Outcome (TO) is a composite quality measure that integrates multiple perioperative endpoints to provide a comprehensive assessment of surgical quality. Although obesity has been associated with adverse outcomes after colorectal surgery, its impact on achieving TO remains unclear, particularly in the era of minimally invasive surgery. This study aimed to evaluate the association between body mass index (BMI) and TO achievement in patients undergoing minimally invasive colorectal cancer surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colo-rectal Cancer | — | UNRESOLVED | — |
| Minimally Invasive Surgical Procedures | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- non-obese grup
- description
- BMI \<30 kg/m²
- label
- obese group
- description
- BMI ≥30 kg/m²
Primary outcomes (1)
- measure
- Demographic, clinical, and perioperative characteristics
- timeFrame
- 30 days
- description
- Age, sex, comorbidity burden assessed by the age-adjusted Charlson Comorbidity Index (CCI) , ASA score , tumor location, neoadjuvant therapy, surgical approach, or postoperative complication rates
Secondary outcomes (1)
- measure
- Textbook Outcome
- timeFrame
- 30 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who underwent curative minimally invasive colorectal cancer resection at a single tertiary referral center between 2021 and 2025 were retrospectively reviewed. All patients were ≥18 years of age. Exclusion Criteria: * Patients undergoing metastatic resections, abdominoperineal resection (APR), Hartmann's procedure, multisegmental or total colectomy, transanal minimally invasive surgery (TAMIS), or palliative procedures were excluded from the analysis.
References
Publications (5)
- BACKGROUNDLara-Romero C, Vilches A, Caunedo-Alvarez A, Hergueta-Delgado P, Lavin-Castejon I, Andrade-Bellido R, Alcain-Martinez G. Better recurrence-free survival after stent bridge to surgery compared to emergency surgery for obstructive left-sided colonic cancer in patients with stage III status of the American Joint Committee on Cancer (AJCC): a bicentric retrospective study. Int J Colorectal Dis. 2019 Jul;34(7):1241-1250. doi: 10.1007/s00384-019-03318-x. Epub 2019 May 25. PMID 31129696
- BACKGROUNDHirata Y, Agnes A, Arvide EM, Robinson KA, To C, Griffith HL, LaRose MD, Munder KM, Mansfield P, Badgwell BD, Ikoma N. Short-Term and Textbook Surgical Outcomes During the Implementation of a Robotic Gastrectomy Program. J Gastrointest Surg. 2023 Jun;27(6):1089-1097. doi: 10.1007/s11605-023-05627-7. Epub 2023 Mar 14. PMID 36917404
- BACKGROUNDRoh CK, Lee S, Son SY, Hur H, Han SU. Textbook outcome and survival of robotic versus laparoscopic total gastrectomy for gastric cancer: a propensity score matched cohort study. Sci Rep. 2021 Jul 28;11(1):15394. doi: 10.1038/s41598-021-95017-3. PMID 34321568
- BACKGROUNDBolger JC, Al Azzawi M, Whooley J, Bolger EM, Trench L, Allen J, Kelly ME, Brosnan C, Arumugasamy M, Robb WB. Surgery by a minimally invasive approach is associated with improved textbook outcomes in oesophageal and gastric cancer. Eur J Surg Oncol. 2021 Sep;47(9):2332-2339. doi: 10.1016/j.ejso.2021.03.240. Epub 2021 Mar 17. PMID 33766456
- BACKGROUNDBusweiler LA, Schouwenburg MG, van Berge Henegouwen MI, Kolfschoten NE, de Jong PC, Rozema T, Wijnhoven BP, van Hillegersberg R, Wouters MW, van Sandick JW; Dutch Upper Gastrointestinal Cancer Audit (DUCA) group. Textbook outcome as a composite measure in oesophagogastric cancer surgery. Br J Surg. 2017 May;104(6):742-750. doi: 10.1002/bjs.10486. Epub 2017 Feb 27. PMID 28240357