Clinical trial · Interventional
Effects of Early Mobilization and Feeding After Lobectomy
The Effect of Early Nutrition and Mobilization From ERAS Protocols on Patient Outcomes in Lung Cancer Patients Undergoing Lobectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled study evaluates the effects of early mobilization and early oral feeding, two components of the Enhanced Recovery After Surgery (ERAS) protocol, on postoperative outcomes in adult patients with lung cancer undergoing lobectomy at Ege University Hospital. Participants were randomly assigned to an intervention group or a control group. In addition to standard postoperative care, participants in the intervention group received an ERAS-based protocol consisting of sitting at the bedside approximately 5.5 hours after surgery, beginning mobilization at 6 hours, and walking at least 100 meters when clinically stable and approved by the surgical team. Oral water intake was started at 6 hours, followed by a full liquid diet at 7 hours and gradual transition to a regular diet at 12 hours if tolerated. Participants in the control group received the clinic's standard postoperative care. The study compares postoperative pain, complications, chest tube duration, length of hospital stay, reoperation, readmission within 30 days, nutritional status, laboratory findings, and quality of life between the two groups. Participants are followed for up to three months after surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Early Mobilization | Other | — | UNRESOLVED |
| Early Oral Feeding | Other | — | UNRESOLVED |
| Standard Postoperative Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- ERAS-Based Early Mobilization and Early Oral Feeding
- description
- Participants received the clinic's standard postoperative care plus an ERAS-based early mobilization and oral feeding protocol. When hemodynamically stable and with approval from the surgical team, participants sat at the bedside approximately 5.5 hours after surgery for 30 minutes, began mobilization at 6 hours, and walked at least 100 meters. Oral water intake began at 6 hours, followed by a full liquid diet at 7 hours and gradual transition to a regular diet at 12 hours if tolerated.
- interventionNames
- Other: Early Mobilization
- Other: Early Oral Feeding
- Other: Standard Postoperative Care
- type
- ACTIVE_COMPARATOR
- label
- Standard Postoperative Care
- description
- Participants received the clinic's standard postoperative care without the additional ERAS-based early mobilization and early oral feeding protocol. Routine care included postoperative monitoring, oxygen support as required, assessment of vital signs, drainage, respiratory function and pain, and coughing and breathing exercises. A liquid diet was initiated at 06:00 on the morning after surgery, and mobilization was performed according to the participant's hemodynamic condition and approval from the surgical team.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 years or older * Diagnosis or suspected diagnosis of lung cancer, including: 1. Histologically or cytologically confirmed lung cancer 2. Radiologically suspected lung cancer pending pathological confirmation * Scheduled to undergo lobectomy * Eastern Cooperative Oncology Group (ECOG) performance status of: 1. ECOG 0 2. ECOG 1 * Ability and willingness to participate, including: 1. Voluntary agreement to participate 2. Ability to provide written informed consent Exclusion Criteria: * Requirement for emergency surgery * Metastatic disease * Severe uncontrolled comorbid disease, including: 1. Cardiac failure 2. Renal failure 3. Hepatic failure * Requirement for mechanical ventilation for 24 hours or longer * History of cranial trauma * Requirement for prolonged bed rest * Neurological conditions, including: 1. Local peripheral neuropathy 2. Central nervous system disease * Impairment affecting participation, including: 1. Cognitive impairment 2. Communication impairment
References
Publications (0)
Data not yet available