Clinical trial · Observational
Shorter Treatment Regimen Implementation Evaluation Study
Evaluation of the Implementation of the Shorter Treatment Regimen for Children and Adolescents With Non-Severe Tuberculosis in Zambia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
"Evaluation of the implementation of the shorter treatment regimen for children and adolescents with non-severe TB in Zambia" is a parallel and convergent mixed methods evaluation study of implementation and clinical outcomes of STR in real-world settings. The study enrolled caregivers and children who were recepients of care on STR, health workers providing STR services, facilities leadership and policy makers. This study aimed to explore acceptability, fidelity, and feasibility of implementing STR in real-world settings in order to optimize program implementation. Additionally, the study aimed to determine the clinical outcomes of patients initiated on the STR in order to ascertain the performance of the regimen in a programmatic setting and contribute to the evidence base for using STR in clinical practice.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Tuberculosis Active | — | UNRESOLVED | — |
| Tuberculosis in Children | — | UNRESOLVED | — |
| Tuberculosis (TB) | — | UNRESOLVED | — |
| Tuberculosis Treatment Effectiveness | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- To explore acceptability, fidelity, and feasibility of implementing STR in real-world settings in order to optimize program implementation.
- timeFrame
- March 2023 to August 2024
- description
- Mixed methods data collection including qualitative interviews and expert review panels
- measure
- To determine the clinical outcomes of children and adolescents aged 3 months to <15 years initiated on the STR in order to ascertain the performance of the regimen in a programmatic setting.
- timeFrame
- March 2023 to August 2024
- description
- Immediate end of treatment outcomes
- measure
- To determine the 1-year post treatment outcomes of children initiated on the STR in order to ascertain the relapse/re-infection free rates.
- timeFrame
- March 2023 to August 2024
- description
- Outcomes after 1 year of treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 3 Months
- Maximum age
- 14 Years
Show eligibility criteria text
Inclusion Criteria: * Children with TB * Children with TB diagnosed between March 2023 to August 2024 Exclusion Criteria: \-
References
Publications (0)
Data not yet available