Clinical trial · Observational
Artificial Intelligence-guided Precision Treatment of High-grade Serous Ovarian Carcinoma
Personalized Precision Diagnosis and Treatment of High-grade Serous Ovarian Carcinoma During the Perioperative Period Assisted by Multi-omics and Artificial Intelligence Models, and Research on the Heterogeneity of Immune Microenvironment
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The subjects of this study are patients with high-grade serous ovarian cancer who have undergone surgical resection. The aim is to construct an artificial intelligence model for predicting postoperative recurrence, metastasis and overall survival of patients based on multimodal data such as surgical pathological images (HE images and IHC images of immune microenvironment-related markers), preoperative baseline imaging data and detailed clinical information of patients. In addition, multi-omics sequencing analysis will be used to deeply explore the heterogeneity of the tumor microenvironment, with the expectation of quantifying the postoperative recurrence risk of patients with high-grade serous ovarian cancer and providing new ideas for the precise diagnosis and treatment of patients with high-grade serous ovarian cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| High-grade Serous Ovarian Carcinoma (HGSOC) | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No Intervention: Observational Cohort | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- High-Risk Group of Recurrence or Metastasis
- description
- AI-assisted patients who have high-risk of postoperative recurrence or metastasis.
- interventionNames
- Other: No Intervention: Observational Cohort
- label
- Low-Risk Group of Recurrence or Metastasis
- description
- AI-assisted patients who have low-risk of postoperative recurrence or metastasis.
- interventionNames
- Other: No Intervention: Observational Cohort
Primary outcomes (1)
- measure
- Disease-free survival
- timeFrame
- through study completion, an average of 1 year
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically confirmed high-grade serous ovarian carcinoma using resection specimens. * Well-preserved surgical paraffin-embedded tumor specimens. * Complete clinical information and survival follow-up data. Exclusion Criteria: * Received preoperative neoadjuvant treatment. * Poor preservation of surgical paraffin specimens. * Incomplete clinical information and survival follow-up data. * With concurrent malignancies other than high-grade serous ovarian carcinoma.
References
Publications (0)
Data not yet available