Clinical trial · Interventional
Tumor Heterogeneity of Renal Tumors Assessed by Multiparametric MRI With Direct Radiological-histopathological Correlation: an Explorative Study
NCT07713654CI-TRIAL-00118650completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study, high-resolution magnetic resonance imaging scans (MRI/mpMRI) were performed before surgical removal of the tumor and then compared with microscopic examinations of the tumor. Instead of looking at just one single area, the study compared many small, spatially correlated sections of the tumor-almost like creating a mini-map of the entire tumor.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Kidney Cancers | Malignant Kidney Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| mpMRI | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Single Arm (MRI)
- description
- mpMRI prior to nephrectomy
- interventionNames
- Diagnostic Test: mpMRI
Primary outcomes (1)
- measure
- Viable tumor fraction
- timeFrame
- Baseline
- description
- Fraction of tumor that is viable
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria: * Patients with confirmed or suspected renal tumor with an approx. size of ≥ 2 cm who are scheduled for clinical MRI examination and surgical resection of the tumor * Informed consent as documented by signature (Informed Consent Form) * Patients ≥18 years of age Exclusion criteria: * Women who are pregnant or breast feeding * Intention to become pregnant during the course of the study and lack of safe contraception * Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia, etc. of the participant * Previous enrolment into the current study * Enrolment of the investigator, his/her family members, employees and other dependent persons * Patients with non-MRI compatible metallic or electronic implants, devices or metallic foreign bodies (cardiac pacemaker, shrapnel, cochlea implants, neurostimulator, or other non-MRI compatible implants). * Patients with known hypersensitivity reactions to MRI contrast agents will undergo the examination without application of a contrast agent
References
Publications (0)
Data not yet available
No reference posted for this study.