Clinical trial · Interventional
Effect of AI-Assisted Expressive Writing on Anxiety, Emotional Distress, and Quality of Life Among Patients Receiving Chemotherapy
The Effect of AI-Assisted Expressive Writing on Anxiety, Emotional Distress, and Quality of Life Among Patients Receiving Chemotherapy: A Mixed-Methods Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to evaluate the effect of an AI-assisted expressive writing intervention on anxiety, emotional distress, and quality of life among patients receiving chemotherapy. A mixed-methods, interventional research design will be employed. Participants will be assigned to either a study group receiving the AI-assisted expressive writing program in addition to routine care or a control group receiving routine care only. Quantitative data will be collected using the Depression Anxiety Stress Scale-21 (DASS-21) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). Qualitative data will be obtained through semi-structured interviews to explore participants' experiences with the intervention. The findings are expected to provide evidence regarding the effectiveness of AI-assisted expressive writing as a supportive strategy for improving psychological well-being and quality of life among patients undergoing chemotherapy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Chemotherapy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Active Comparator: Routine Care Group | Other | — | UNRESOLVED |
| AI-Assisted Expressive Writing | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- AI-Assisted Expressive Writing Group
- description
- Participants in this group will receive routine chemotherapy care in addition to the AI-assisted expressive writing program. The intervention will be delivered through guided writing sessions using an artificial intelligence platform designed to facilitate emotional expression and reflection.
- interventionNames
- Behavioral: AI-Assisted Expressive Writing
- type
- ACTIVE_COMPARATOR
- label
- Routine Care Group
- interventionNames
- Other: Active Comparator: Routine Care Group
Primary outcomes (2)
- measure
- Change in Anxiety and Emotional Distress Scores
- timeFrame
- Baseline (Day 1) and Week 4 after intervention
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients aged 18 years and above. * Diagnosed with any type of cancer and currently receiving chemotherapy treatment. * Able to read and write Arabic. * Able to communicate and express thoughts and feelings. * Have access to a smartphone, tablet, or computer with internet connectivity. * Willing to participate in the study and provide informed consent. Exclusion Criteria: * Diagnosed with severe psychiatric disorders (e.g., psychosis or schizophrenia). * Having cognitive impairment that interferes with understanding or communication. * Currently receiving structured psychological therapy during the study period. * Unable to complete the study questionnaires or intervention sessions. * Refusal to participate or withdrawal from the study at any time.
References
Publications (0)
Data not yet available