Clinical trial · Observational
ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This was an observational study, with a descriptive and comparative portion. The descriptive analysis, a large single center experience, examined bleeding complications, infectious rates, and survival outcomes in patients under 18 years old with an underlying oncologic diagnosis and/or hematopoietic stem cell transplant on Extracorporeal membrane oxygenation (ECMO). In a small multicenter cohort, the comparative analysis evaluated survival outcomes in this population with respiratory failure in the presence and absence of ECMO. Children's Mercy Kansas City served as the ECMO cohort; Cincinnati Children's Hospital Medical Center served as the matched non-ECMO cohort.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ECMO Outcomes | — | UNRESOLVED | — |
| Hematopoetic Stem Cell Transplant | — | UNRESOLVED | — |
| Malignancies, Hematologic | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
| Respiratory Failure (Pediatric Patients) | — | UNRESOLVED | — |
| Solid Tumor Malignancies | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Extracorporeal membrane oxygenation (ECMO) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- ECMO Cohort
- description
- Eleven patients under 18 years old with an underlying oncologic diagnosis and/or hematopoietic stem cell transplant received Extracorporeal membrane oxygenation (ECMO) as a rescue therapy for respiratory failure. Children's Mercy Hospital served as the ECMO cohort.
- interventionNames
- Other: Extracorporeal membrane oxygenation (ECMO)
- label
- Non-ECMO Cohort
- description
- Eleven patients under 18 years old with an underlying oncologic diagnosis and/or hematopoietic stem cell transplant received conventional therapies for management of respiratory failure. Cincinnati Children's Hospital Medical Center served as the non-ECMO cohort.
Primary outcomes (1)
- measure
- Comparison of survival rates in pediatric patients with an underlying malignancy and/ or hematopoietic stem cell transplant in the presence and absence of ECMO support
- timeFrame
- Admission until hospital discharge, average of 46 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 4 Weeks
- Maximum age
- 17 Years
Show eligibility criteria text
Inclusion Criteria: * Less than 18 years old * Admitted to the PICU for respiratory failure (2015-2023) * Underlying oncologic diagnosis and/or hematopoietic stem cell transplant * Mechanical ventilation
References
Publications (0)
Data not yet available