Clinical trial · Observational
Predictive Model For Anastomotic Leakage After Colorectal Cancer Surgery
Simplified Predictive Model For Anastomotic Leakage After Colorectal Cancer Surgery: A Pilot Retrospective Study
NCT07709923CI-TRIAL-00118455Doesn't existcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This pilot study aimed to develop a simplified early postoperative model for AL risk stratification using readily available clinical and laboratory variables.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal (Colon or Rectal) Cancer | Childhood Colorectal Carcinoma | ALIAS | 0.90 |
| Leak, Anastomotic | — | UNRESOLVED | — |
| Surgery Complications | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Patients underwent elective colorectal surgery
- description
- number of leakage
Primary outcomes (1)
- measure
- Number of Participants Who Developed Clinically Significant Anastomotic Leakage Requiring Surgical Reintervention and/or Stoma Creation
- timeFrame
- 2 years
- description
- Number of participants who developed clinically significant anastomotic leakage after colorectal cancer surgery. Anastomotic leakage was defined as an anastomotic defect confirmed by clinical, radiological, intraoperative, or postoperative findings requiring surgical reintervention and/or stoma creation.
Secondary outcomes (5)
- measure
- Area Under the Receiver Operating Characteristic Curve (AUC-ROC) of the Predictive Model
- timeFrame
- 2 years
- description
- Discriminative ability of the simplified logistic regression model for predicting clinically significant anastomotic leakage
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. colorectal cancer resection 2. construction of a primary anastomosis 3. availability of clinical and laboratory data from the first postoperative day Exclusion Criteria: 1. staged procedures without primary anastomosis 2. Hartmann's procedure 3. protective stoma at the index operation 4. incomplete data for the variables required for model construction.
References
Publications (0)
Data not yet available
No reference posted for this study.