Clinical trial · Observational
The Correlation of Postoperative Polyp Recurrence and Colorectal Cancer
Postoperative Endoscopic Polyp Recurrence Correlation With Pathological Status Classification of Colorectal Cancer: a Multicenter, Retrospective Cohort Open-label Study
NCT07708415CI-TRIAL-00118272not yet recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Polyps | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic polypectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Postoperative endoscopic polyp recurrence of colorectal cancer
- description
- Corhort of colorectal cancer patients undergoing colonoscopy follow-up after surgery
- interventionNames
- Procedure: Endoscopic polypectomy
Primary outcomes (2)
- measure
- Adenoma recurrence after colorectal surgery
- timeFrame
- Postoperative；follow up till 5 years
- description
- Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence
- measure
- Colitisafter colorectal surgery
- timeFrame
- Postoperative；follow up till 5 years
- description
- Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: Patients who underwent radical surgery for colon cancer at Gansu Provincial People's Hospital from January 2015 to December 2024 and regularly completed colonoscopy follow-up after surgery were selected as the research subjects. Inclusion criteria: Diagnosed with colon cancer through histopathological examination ; Undergoing radical R0 resection ； Complete Colonoscopy follow-up after surgery less than 12 months. Exclusion Criteria: With adenomatous polyposis , Lynch syndrome and Peutz-Jeghers syndrome； Combined inflammatory bowel disease; Polyp were present before surgery and have not been completely removed； With distant metastasis or local recurrence； Clinical data is missing and can not be analyzed.
References
Publications (4)
- BACKGROUNDGaljart B, Hoppener DJ, Aerts JGJV, Bangma CH, Verhoef C, Grunhagen DJ. Follow-up strategy and survival for five common cancers: A meta-analysis. Eur J Cancer. 2022 Oct;174:185-199. doi: 10.1016/j.ejca.2022.07.025. Epub 2022 Aug 27. PMID 36037595
- RESULTIJspeert JEG, Bretthauer M, Jover R, Dekker E; Dutch colonoscopy surveillance working group. Balancing benefit and burden: rethinking post-polypectomy colonoscopy surveillance strategies. Lancet Gastroenterol Hepatol. 2026 Aug;11(8):720-726. doi: 10.1016/S2468-1253(26)00128-7. Epub 2026 Jun 19. PMID 42320508
- RESULTEbert MP, Reichermeier S, Klug L, Lynen Jansen P, Pox C. Clinical Practice Guideline: Colorectal Cancer-Diagnosis, Treatment, Prevention, and Long-Term Follow-Up Care. Dtsch Arztebl Int. 2025 Dec 26;122(26):729-734. doi: 10.3238/arztebl.m2025.0196. Epub 2025 Dec 26. PMID 41195479
- RESULTLaven-Law G, Symonds EL, Simpson K, Coats M, De Silva M, Hollington P, Cock C, Wassie MM. Risk of Advanced Colorectal Neoplasia at Follow-up Colonoscopy After Synchronous Adenoma and Clinically Significant Serrated Polyp. Clin Gastroenterol Hepatol. 2026 Feb;24(2):544-553. doi: 10.1016/j.cgh.2025.07.023. Epub 2025 Aug 5. PMID 40774589