Clinical trial · Observational
LUCINAE Registry: Thoracic Cancers During Pregnancy
LUCINAE: LUng and Thoracic Cancers In pregNAncy rEgistry
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The LUCINAE Registry is an international, multicenter observational study collecting data on patients with thoracic cancers (including lung cancer) who are expecting a child. This includes women diagnosed during pregnancy, women who become pregnant during or after cancer, and men receiving cancer treatment at the time their partner conceives. Because thoracic cancers during pregnancy are rare, there is limited information to guide clinical decisions. This registry aims to describe patient characteristics, diagnostic approaches, treatments, and maternal and fetal outcomes. Data are collected retrospectively and prospectively from participating centers. The results of this registry are expected to improve understanding of thoracic cancers in this setting and support the development of future clinical recommendations.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer During Pregnancy | Lung Neoplasm | PROBABILISTIC | 0.70 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Thoracic Cancer | Malignant Thoracic Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Cohort A
- description
- Retrospective patients: patients who are included in the registry only after death.
- label
- Cohort B
- description
- Prospective patients: patients who are currently treated at the participating site or will be diagnosed during the enrollment
Primary outcomes (5)
- measure
- Timing of diagnosis
- timeFrame
- At the moment of patient enrolment
- description
- Timing of cancer diagnosis with respect to the onset of pregnancy.
- measure
- Modality of diagnosis
- timeFrame
- At the moment of patient enrolment
- description
- Method used for cancer diagnosis.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 1\. All patients with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities) and pregnancy (positive pregnancy test) including: 1. Patients receiving a diagnosis of thoracic cancer during pregnancy 2. Patients who became pregnant while having active thoracic cancer 3. Patients previously treated for a thoracic cancer and becoming pregnant in the 5 years following end of treatment OR Men with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities), who were undergoing active oncological treatment at the time their partner conceived their child. * 2\. Available information about pregnancy outcomes * 3\. Age ≥ 18 years Exclusion Criteria: * 1\. Patient missing data about thoracic cancer stage and diagnosis * 2\. For retrospective patients, documented refusal to the use of clinical data for research purposes
References
Publications (0)
Data not yet available