Clinical trial · Interventional
EEG-Guided Cognitive Function Preservation in Patients With Brain Tumors
A Prospective Single-Arm Study of EEG-Based Neural Signal Decoding for Cognitive Function Preservation in Patients Undergoing Brain Tumor Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Brain tumors and their surgical treatment may impair cognitive function, affecting patients' quality of life. This prospective single-arm study aims to evaluate the feasibility and clinical utility of an EEG-based neural signal decoding strategy for cognitive function preservation in patients undergoing brain tumor surgery. Participants will undergo standardized neuropsychological assessments together with preoperative, intraoperative, and postoperative electrophysiological recordings. The study will investigate whether EEG-based neural decoding can improve objective cognitive function assessment and support individualized functional preservation during brain tumor surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Neoplasm | Brain Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Brain Tumor Adult | Brain Neoplasm | ALIAS | 0.85 |
| Glioma | Glioma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EEG-Based Neural Signal Decoding Strategy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- EEG-Guided Cognitive Function Preservation
- description
- Participants undergoing brain tumor surgery will receive the EEG-based neural signal decoding strategy in addition to standard surgical management for individualized cognitive function preservation. Cognitive outcomes will be evaluated using standardized neuropsychological assessments.
- interventionNames
- Procedure: EEG-Based Neural Signal Decoding Strategy
Primary outcomes (2)
- measure
- Mini-Mental State Examination (MMSE) Total Score
- timeFrame
- Baseline, postoperative 1 week, postoperative 1 month, and postoperative 3 months
- description
- Cognitive function assessed using the Mini-Mental State Examination (MMSE). The total score ranges from 0 to 30, with higher scores indicate better cognitive function.
- measure
- Montreal Cognitive Assessment (MoCA) Total Score
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 years to 75 years. * Patients diagnosed with brain glioma and scheduled for surgical treatment. * Conscious and able to understand study procedures. * Able to complete neuropsychological assessments. * Willing to participate and provide written informed consent. Exclusion Criteria: * Severe dysfunction of major organs (heart, lung, liver, or kidney). * Severe psychiatric disorders or cognitive impairment. * Severe language impairment preventing completion of study procedures. * Any other condition judged by the investigator to make participation inappropriate.
References
Publications (0)
Data not yet available