Clinical trial · Interventional
Endoscopic Assisted Latissimus Dorsi Musculocutaneous Flap for Breast Reconstruction
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective single-arm case series evaluates the feasibility, safety, and clinical outcomes of endoscopic-assisted latissimus dorsi musculocutaneous flap harvest for breast reconstruction. The study includes women with post-oncologic or post-burn breast deformities requiring autologous tissue reconstruction with a skin paddle measuring 6 cm or less in its greatest dimension. The primary objective is to assess the feasibility of minimally invasive flap harvest while preserving reconstructive effectiveness. Secondary outcomes include flap viability, operative time, postoperative pain, drain duration, donor-site morbidity, scar quality, complications, and patient satisfaction. Patients are followed for one year after surgery, with clinical assessment and patient-reported outcome measures used to evaluate reconstructive and aesthetic results.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acquired Breast Deformity | — | UNRESOLVED | — |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Post Burn Breast Deformities | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic-Assisted Latissimus Dorsi Musculocutaneous Flap Harvest | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Endoscopic-Assisted Latissimus Dorsi Musculocutaneous Flap Reconstruction
- description
- Participants underwent breast reconstruction using an endoscopic-assisted latissimus dorsi musculocutaneous flap harvested through a limited donor-site incision. The procedure was performed to reconstruct post-oncologic or post-burn breast deformities while minimizing donor-site scarring and morbidity. All participants received the same surgical intervention and were followed prospectively to evaluate surgical, aesthetic, and patient-reported outcomes.
- interventionNames
- Procedure: Endoscopic-Assisted Latissimus Dorsi Musculocutaneous Flap Harvest
Primary outcomes (1)
- measure
- Number of patients with successful endoscopic-assisted latissimus dorsi musculocutaneous flap harvest and reconstruction without conversion to open technique
- timeFrame
- During surgery through 30 days postoperatively
- description
- Success was defined as completion of endoscopic-assisted harvest and transfer of the latissimus dorsi musculocutaneous viable flap without conversion to a conventional open harvest.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients aged 18 to 65 years. * Patients with post-oncologic or post-burn breast deformities requiring autologous breast reconstruction. * Patients requiring reconstruction with a latissimus dorsi musculocutaneous flap incorporating a skin paddle measuring ≤6 cm in its greatest dimension. * Defects considered unsuitable for correction with local tissue rearrangement. * Intact latissimus dorsi muscle and thoracodorsal vascular pedicle. * Ability to provide written informed consent and comply with the study follow-up schedule. Exclusion Criteria: * Age younger than 18 years or older than 65 years. * Body mass index (BMI) \>35 kg/m². * Uncontrolled medical comorbidities or immunosuppressive conditions. * Absence of a skin defect requiring reconstruction. * Cutaneous defects requiring a skin paddle \>6 cm in its greatest dimension. * Inadequate oncologic control or evidence of active disease. * Ongoing adjuvant chemotherapy or radiotherapy at the time of reconstruction. * Previous thoracic surgery or trauma compromising the latissimus dorsi muscle or thoracodorsal vascular pedicle. * Inability or unwillingness to comply with study follow-up.
References
Publications (0)
Data not yet available