Clinical trial · Observational
EWALL-PH OBSERVARTORY 2022
AN OBSERVATORY FOR PATIENTS AGED 18 YEARS AND OVER WITH PHILADELPHIA CHROMOSOME POSITIVE (PH+ OR BCR::ABL1+) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) AND TREATED WITH THE COMBINATION OF BCR::ABL1 INHIBITORS AND CHEMOTHERAPY AND/OR CORTICOSTEROIDS AND/OR A MONOCLONAL ANTIBODY.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
An observatory for patients aged 18 years and over with Philadelphia chromosome positive (Ph+ or BCR::ABL1) acute lymphoblastic leukemia (ALL) and treated with the combination of BCR::ABL1 inhibitors and chemotherapy and/or corticosteroids and/or a monoclonal antibody.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Overall survival by 12 months
- timeFrame
- 12 months
Secondary outcomes (10)
- measure
- overal survival by 36 months
- timeFrame
- 36 months
- measure
- proportion of complete remission
- timeFrame
- 36 months
- measure
- the molecular response defined by BCR//ABL1/ABL1 ratio in bone marrow and/or peripheral blood
- timeFrame
- 36 months
- measure
- the molecular response defined by IGTR quantification proportion in bone marrow and/or peripheral blood
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Male or female patients ≥ 18 years 2. Philadelphia chromosome or BCR::ABL1 positive acute lymphoblastic leukaemia 3. Treatment with the combination of BCR::ABL1 inhibitors and chemotherapy and/or corticotherapy and/or a monoclonal antibody Exclusion Criteria: 1. Patients deceded and having previously refused data collection 2. Not included in a prospective clinical trial
References
Publications (0)
Data not yet available