Clinical trial · Observational
Association Between 4D MRI Parameters and the Clinical Characteristics and Prognosis of Major Chronic Diseases
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
Cancer and cardiovascular diseases are among the leading causes of morbidity and mortality worldwide. Advanced imaging techniques such as 4D magnetic resonance imaging (MRI) enable quantitative assessment of hemodynamic and functional parameters beyond conventional imaging. The aim of this study is to evaluate the association between 4D MRI derived parameters and the occurrence, severity, and prognosis of major chronic diseases, and to explore their potential role as imaging biomarkers.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cardiac Magnetic Resonance Imaging | — | UNRESOLVED | — |
| Cardiovascular Disease | — | UNRESOLVED | — |
| Neoplasm | Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Ulsan University Hospital, 4D MRI cohort
- description
- Adult patients aged 19 years and older undergoing clinically indicated Cardiac MRI at Ulsan University Hospital who provide written informed consent and undergo an additional 4D MRI sequence during the same imaging session.
Primary outcomes (1)
- measure
- Incidence of Major Adverse Cardiovascular Events (MACE)
- timeFrame
- up to 10 years
- description
- Incidence of major adverse cardiovascular events, including cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, hospitalization for heart failure during the follow-up period
Secondary outcomes (2)
- measure
- Peak Wall Shear Stress
- timeFrame
- Perioperative/Periprocedural
- description
- peak wall shear stress measured in the ascending aorta using 4D flow MRI
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: * Adults aged 19 years and older undergoing clinically indicated Cardiac MRI at Ulsan University Hospital * Participants who undergo an additional 4D MRI sequence during the same imaging session * Participants who are able to understand the study and provide written informed consent Exclusion Criteria: * Individuals aged \< 19 years * Individuals with cognitive impairment or communication difficulties unable to provide informed consent * Poor-quality MRI images that are not suitable for analysis * Individuals deemed inappropriate for study participation by the investigator
References
Publications (0)
Data not yet available