Clinical trial · Interventional
Effect of Virtual Reality-Guided Imagery on Pain, Anxiety, and Fatigue in Cancer Patients Undergoing Chemotherapy
Effect of Virtual Reality Guided Imagery on Pain, Anxiety, and Fatigue in Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled trial aims to evaluate the effectiveness of virtual reality-guided imagery in reducing pain, anxiety, and fatigue among female breast cancer patients undergoing adjuvant chemotherapy. Participants will be randomly assigned to either an intervention group receiving virtual reality-guided imagery in addition to routine care, or a control group receiving routine care
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anxiety | — | UNRESOLVED | — |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Chemotherapy | — | UNRESOLVED | — |
| Fatigue | — | UNRESOLVED | — |
| Guided Imagery | — | UNRESOLVED | — |
| Pain | — | UNRESOLVED | — |
| Virtual Reality | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Virtual Reality-Guided Imagery | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Virtual Reality-Guided Imagery plus Routine Care
- description
- Participants in this group will receive guided virtual reality mindfulness sessions, in addition to their routine chemotherapy care. This intervention is a non-pharmaceutical supportive approach designed to reduce pain, anxiety, and fatigue through immersive guided mindfulness and relaxation during chemotherapy cycles.
- interventionNames
- Device: Virtual Reality-Guided Imagery
- type
- NO_INTERVENTION
- label
- Routine Care Only
- description
- Participants in this arm will receive routine chemotherapy care only without virtual reality-guided imagery intervention.
Primary outcomes (1)
- measure
- Pain intensity
- timeFrame
- Baseline; immediately after the first intervention; before the second intervention (Week 3); immediately after the second intervention (Week 3)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients aged 18 years or older. * Histologically confirmed breast cancer. * Stage I, II, or III breast cancer. * Underwent surgery as the initial treatment and are scheduled to receive the first cycle of adjuvant chemotherapy, with or without biologic therapy (e.g., AC or TC regimens). * Able to read, write, and communicate. * Able and willing to use a virtual reality headset. * Able to provide written informed consent. Exclusion Criteria: * Visual or hearing impairment that prevents the use of virtual reality. * Serious neurological or psychiatric disorders. * Current participation in other non-pharmacological interventions (e.g., meditation or relaxation therapy) that could influence the study outcomes. * Previous experience with virtual reality-guided imagery. * Use of analgesics, anxiolytics, or other medications during the intervention that may affect the study outcomes.
References
Publications (0)
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